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[HTML][HTML] Burn-induced local and systemic immune response: systematic review and meta-analysis of animal studies
Because burn injuries are often followed by a derailed immune response and excessive
inflammation, a thorough understanding of the occurring reactions is key to preventing …
inflammation, a thorough understanding of the occurring reactions is key to preventing …
[HTML][HTML] Kinetics of inflammatory mediators in the immune response to burn injury: Systematic review and meta-analysis of animal studies
Burns are often accompanied by a dysfunctional immune response, which can lead to
systemic inflammation, shock, and excessive scarring. The objective of this study was to …
systemic inflammation, shock, and excessive scarring. The objective of this study was to …
A microsatellite DNA-derived oligodeoxynucleotide attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting the HMGB1-TLR4-NF-κB signaling …
C Zhang, H Wang, H Wang, S Shi, P Zhao… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) with uncontrolled inflammatory response has high morbidity and
mortality rates in critically ill patients. Pathogen-associated molecular patterns (PAMPs) are …
mortality rates in critically ill patients. Pathogen-associated molecular patterns (PAMPs) are …
Massively recruited sTLR9+ neutrophils in rapidly formed nodules at the site of tumor cell inoculation and their contribution to a pro-tumor microenvironment
M Kou, W Lu, M Zhu, K Qu, L Wang, Y Yu - Cancer Immunology …, 2023 - Springer
Neutrophils exert either pro-or anti-tumor activities. However, few studies have focused on
neutrophils at the tumor initiation stage. In this study, we unexpectedly found a …
neutrophils at the tumor initiation stage. In this study, we unexpectedly found a …
Expression levels of interferon regulatory factor 5 (IRF5) and related inflammatory cytokines associated with severity, prognosis, and causative pathogen in patients …
X Wang, J Guo, Y Wang, Y **ao… - … medical journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Background Community-acquired pneumonia (CAP) is a common disease with significant
morbidity and mortality. Interferon regulatory factor 5 (IRF5), which induces type I interferons …
morbidity and mortality. Interferon regulatory factor 5 (IRF5), which induces type I interferons …
The adjuvanticity of manganese for microbial vaccines via activating the IRF5 signaling pathway
C Cui, S Wang, W Lu, Y Wang, J Li, K Qu… - Biochemical …, 2021 - Elsevier
Abstract Manganese (Mn 2+) has been reported to activate macrophages and NK cells, and
to induce the production of type-I interferons (IFNs) by activating the cGAS-STING pathway …
to induce the production of type-I interferons (IFNs) by activating the cGAS-STING pathway …
IRF5 promotes the polarization of M1 macrophages and aggravates lung inflammation in connective tissue disease-related interstitial lung disease (CTD-ILD) by …
S Chen, Q Ming, X Wang - 2023 - researchsquare.com
Background Interferon regulatory factor 5 (IRF5) plays a vital role in proinflammatory M1
macrophages and is involved in their polarization. We aimed to explore the mechanism of …
macrophages and is involved in their polarization. We aimed to explore the mechanism of …
Evaluacion de Respuestas Inmunes Usando Oligodesoxinucleotido como Adyuvantes.
B Pérez, A Díaz, S López - Investigación Clínica, 2020 - go.gale.com
En los últimos años, se ha prestado una atención considerable a la inducción de respuestas
inmunes de la mucosa como medio para prevenir la transmisión de enfermedades …
inmunes de la mucosa como medio para prevenir la transmisión de enfermedades …