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[HTML][HTML] Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm
Gastrointestinal (GI) carcinomas are a group of cancers affecting the GI tract and digestive
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …
Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment
D Ye, Z Shen, S Zhou - Cancer management and research, 2019 - Taylor & Francis
miRNAs are single-stranded small RNAs that do not encode proteins. They can combine
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis
Gap junctional communication between cancer cells and blood capillary cells is crucial to
tumor growth and invasion. Gap junctions may transfer microRNAs (miRs) among cells …
tumor growth and invasion. Gap junctions may transfer microRNAs (miRs) among cells …
MicroRNAs‐dependent regulation of PPARs in metabolic diseases and cancers
Peroxisome proliferator‐activated receptors (PPARs) are a family of ligand‐dependent
nuclear receptors, which control the transcription of genes involved in energy homeostasis …
nuclear receptors, which control the transcription of genes involved in energy homeostasis …
Potential roles of microRNAs and ROS in colorectal cancer: diagnostic biomarkers and therapeutic targets
As one of the most commonly diagnosed cancers worldwide, colorectal adenocarcinoma
often occurs sporadically in individuals aged 50 or above and there is an increase among …
often occurs sporadically in individuals aged 50 or above and there is an increase among …
Implications of miR cluster 143/145 as universal anti-oncomiRs and their dysregulation during tumorigenesis
Tumorigenesis is a multistep process, de-regulated due to the imbalance of oncogenes as
well as anti-oncogenes, resulting in disruption of tissue homeostasis. In many cases the …
well as anti-oncogenes, resulting in disruption of tissue homeostasis. In many cases the …
Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1
W Wang, G Ji, X **ao, X Chen, WW Qin, F Yang… - …, 2016 - pmc.ncbi.nlm.nih.gov
MiR-145 is a tumor-suppressive microRNA that participates in the malignant progression of
colorectal cancer (CRC). Although miR-145 has been reported to inhibit proliferation and to …
colorectal cancer (CRC). Although miR-145 has been reported to inhibit proliferation and to …
Identification of a novel PPAR β/δ/miR‐21‐3p axis in UV‐induced skin inflammation
Although excessive exposure to UV is widely recognized as a major factor leading to skin
perturbations and cancer, the complex mechanisms underlying inflammatory skin disorders …
perturbations and cancer, the complex mechanisms underlying inflammatory skin disorders …
miR-145 suppresses colorectal cancer cell migration and invasion by targeting an ETS-related gene
S Li, X Wu, Y Xu, S Wu, Z Li, R Chen… - Oncology …, 2016 - spandidos-publications.com
Abstract MicroRNA-45 (miR-145) has been demonstrated to be downregulated in various
cancer types including colorectal cancer (CRC). However, the function of miR‑145 in CRC …
cancer types including colorectal cancer (CRC). However, the function of miR‑145 in CRC …
[HTML][HTML] The interplay between colon cancer cells and tumour-associated stromal cells impacts the biological clock and enhances malignant phenotypes
Cancer cells interrelate with the bordering host microenvironment that encompasses the
extracellular matrix and a nontumour cellular component comprising fibroblasts and immune …
extracellular matrix and a nontumour cellular component comprising fibroblasts and immune …