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Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors
ID Neumann, R Landgraf - Trends in neurosciences, 2012 - cell.com
Oxytocin and vasopressin are regulators of anxiety, stress-co**, and sociality. They are
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …
released within hypothalamic and limbic areas from dendrites, axons, and perikarya …
Neuropathology of stress
Environmental challenges are part of daily life for any individual. In fact, stress appears to be
increasingly present in our modern, and demanding, industrialized society. Virtually every …
increasingly present in our modern, and demanding, industrialized society. Virtually every …
[HTML][HTML] The human hypothalamus in mood disorders: The HPA axis in the center
AM Bao, DF Swaab - IBRO reports, 2019 - Elsevier
There are no specific structural neuropathological hallmarks found in the brain of mood
disorders. Instead, there are molecular, functional and structural alterations reported in many …
disorders. Instead, there are molecular, functional and structural alterations reported in many …
Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress
In the present study, we have examined the behavioral and biochemical effect of induction of
psychological stress using a modified version of the resident-intruder model for social stress …
psychological stress using a modified version of the resident-intruder model for social stress …
Oxidative stress in psychiatric disorders: evidence base and therapeutic implications
Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …
50 years of hurdles and hope in anxiolytic drug discovery
Anxiety disorders are the most prevalent group of psychiatric diseases, and have high
personal and societal costs. The search for novel pharmacological treatments for these …
personal and societal costs. The search for novel pharmacological treatments for these …
Both oxytocin and vasopressin are mediators of maternal care and aggression in rodents: from central release to sites of action
In the mammalian peripartum period, the activity of both the brain oxytocin and vasopressin
system is elevated as part of the physiological adaptations occurring in the mother. This is …
system is elevated as part of the physiological adaptations occurring in the mother. This is …
Neuronal circuits of fear extinction
Fear extinction is a form of inhibitory learning that allows for the adaptive control of
conditioned fear responses. Although fear extinction is an active learning process that …
conditioned fear responses. Although fear extinction is an active learning process that …
The age of anxiety: role of animal models of anxiolytic action in drug discovery
JF Cryan, FF Sweeney - British journal of pharmacology, 2011 - Wiley Online Library
Anxiety disorders are common, serious and a growing health problem worldwide. However,
the causative factors, aetiology and underlying mechanisms of anxiety disorders, as for most …
the causative factors, aetiology and underlying mechanisms of anxiety disorders, as for most …
Vasopressin: behavioral roles of an “original” neuropeptide
Vasopressin (Avp) is mainly synthesized in the magnocellular cells of the hypothalamic
supraoptic (SON) and paraventricular nuclei (PVN) whose axons project to the posterior …
supraoptic (SON) and paraventricular nuclei (PVN) whose axons project to the posterior …