Despite the significant medical and technical improvements in the field of dialytic renal
replacement modalities, morbidity and mortality are excessively high among patients with …

In recent years there has been an increasing interest in expanded hemodialysis (HDx), an
emerging renal replacement therapy based on the use of medium cut-off membranes …

During the last decades, various strategies have been optimized to enhance clearance of a
variable spectrum of retained molecules to ensure hemodynamic tolerance to fluid removal …

Background This systematic review was performed to identify recent published comparative
evidence on the efficacy, effectiveness, and safety of expanded hemodialysis (HDx) versus …

Hemodiafiltration with endogenous reinfusion of the ultrafiltrate (HFR) is a dialysis technique
characterized by a resin cartridge with adsorptive properties that combines the mechanisms …

Uremic toxins accumulate in patients affected by renal failure and can deposit in different
organs, including the kidneys and heart. Given their physicochemical characteristics, uremic …

Extended cut-off filtration by medium cut-off membranes (MCO) has been shown to be safe
in maintenance hemodialysis (HD). The notion of using them for the control of chronic low …

Despite recent technological advances, current extracorporeal blood purification therapies
(EBPT) present significant limitations both in chronic and acute renal failure.[1, 2] This …

Tuning the pore size distribution of hemodialysis membranes is essential for the
membrane's selectivity and significantly affects the quality of the dialysis treatment. Tailoring …

Solutes that accumulate when the kidneys fail range in size from about 40 to 40,000 Da.
Their dialytic clearance tends to decrease as their size increases. Disproportionate …