Animal models of multiple sclerosis—potentials and limitations

E Mix, H Meyer-Rienecker, HP Hartung… - Progress in neurobiology, 2010 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is still the most widely accepted animal
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …

DNA microarrays in herbal drug research

P Chavan, K Joshi… - … Based Complementary and …, 2006 - Wiley Online Library
Natural products are gaining increased applications in drug discovery and development.
Being chemically diverse they are able to modulate several targets simultaneously in a …

Transcriptomic point of departure determination: a comparison of distribution-based and gene set-based approaches

E Costa, KJ Johnson, CA Walker, JM O'Brien - Frontiers in Genetics, 2024 - frontiersin.org
A key step in assessing the potential human and environmental health risks of industrial and
agricultural chemicals is to determine the toxicity point of departure (POD), which is the …

Prospects of optical biosensors for emerging label-free RNA analysis

LG Carrascosa, CS Huertas, LM Lechuga - Trac Trends in Analytical …, 2016 - Elsevier
RNA is critical in countless cellular processes, and researchers are constantly discovering
new types and attributing them different roles. Consequently, a growing interest in efficient …

Transportation stress alters the circulating steroid environment and neutrophil gene expression in beef bulls

KRB Sporer, L ** of cognitive decline
B Wilmot, SK McWeeney, RR Nixon, TJ Montine… - Neurobiology of …, 2008 - Elsevier
The ability to maintain cognitive function during aging is a complex process subject to
genetic and environmental influences. Alzheimer's disease (AD) is the most common …

Process for improved protein expression by strain engineering

TM Ramseier, H **, CH Squires - US Patent 8,603,824, 2013 - Google Patents
3,844,893 A 10, 1974 Hitzman 3,878,093 A 4, 1975 Kanani et al. 4,169,010 A 9, 1979
Marwill 4,551,433 A 11, 1985 DeBoer 4,595,658 A 6, 1986 Zinder et al. 4,637,980 A 1, 1987 …