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A review of the role of flavonoids in peptic ulcer (2010–2020)
C Serafim, ME Araruna, EA Júnior, M Diniz… - Molecules, 2020 - mdpi.com
Peptic ulcers are characterized by erosions on the mucosa of the gastrointestinal tract that
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …
Fucoidan mitigates gastric ulcer injury through managing inflammation, oxidative stress, and NLRP3-mediated pyroptosis
This study aimed to elucidate the gastro-protective effect of fucoidan against ethanol-
induced gastric ulcer mediated via NLRP3-induced pyroptosis as an underlying mechanism …
induced gastric ulcer mediated via NLRP3-induced pyroptosis as an underlying mechanism …
Drug discovery strategies for modulating oxidative stress in gastrointestinal disorders
Introduction Due to the ever-growing incidence of gastrointestinal disorders accompanied by
substantial economic impact, it is of great importance to manage these conditions globally …
substantial economic impact, it is of great importance to manage these conditions globally …
Safranal, a constituent of saffron, exerts gastro-protective effects against indomethacin-induced gastric ulcer
E Tamaddonfard, A Erfanparast, AA Farshid, M Imani… - Life sciences, 2019 - Elsevier
Aims Several natural products have been evaluated for management of gastric ulcer
induced by non-steroidal anti-inflammatory drugs. Safranal, a plant-derived chemical, has a …
induced by non-steroidal anti-inflammatory drugs. Safranal, a plant-derived chemical, has a …
[HTML][HTML] Malvidin protects against and repairs peptic ulcers in mice by alleviating oxidative stress and inflammation
FL Fagundes, QC Pereira, ML Zarricueta… - Nutrients, 2021 - mdpi.com
Peptic ulcer episodes cause damage to the stomach and intestine, with inflammatory cell
infiltration and oxidative stress as the main players. In this study, we investigated the …
infiltration and oxidative stress as the main players. In this study, we investigated the …
ALDH2 ameliorates ethanol-induced gastric ulcer through suppressing NLPR3 inflammasome activation and ferroptosis
Y Zhang, Z Yuan, J Chai, D Zhu, X Miao, J Zhou… - Archives of biochemistry …, 2023 - Elsevier
Gastric ulcer (GU) is a prevalent and life-threating gastrointestinal disorder. Aldehyde
dehydrogenase 2 (ALDH2) is a pivotal component of alcohol metabolism which has been …
dehydrogenase 2 (ALDH2) is a pivotal component of alcohol metabolism which has been …
The effects of dragon fruit (Hylocereus polyrhizus) extract on indomethacin‐induced stomach ulcer in rats
The aim of this study was to investigate the effects of red dragon fruit (Hylocereus polyrhizus)
extract (DFE) on the stomach in ulcer model induced by indomethacin in rats. Effects of DFE …
extract (DFE) on the stomach in ulcer model induced by indomethacin in rats. Effects of DFE …
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway
Aims Gastric ulcer is a continuous worldwide threat that inquires protective agents.
Olmesartan (OLM) has potent anti-oxidant and anti-inflammatory characters, yet having …
Olmesartan (OLM) has potent anti-oxidant and anti-inflammatory characters, yet having …
Gastroprotective effect of topiramate on indomethacin‐induced peptic ulcer in rats: Biochemical and histological analyses
A Jafari, N Andishfar, Z Esmaeilzadeh… - Basic & Clinical …, 2022 - Wiley Online Library
Topiramate is an anticonvulsant drug effective against a wide range of seizures and
epilepsies. The present study was conducted to investigate the possible protective effect of …
epilepsies. The present study was conducted to investigate the possible protective effect of …
Interplay of biochemical, genetic, and immunohistochemical factors in the etio-pathogenesis of gastric ulcer in rats: a comparative study of the effect of pomegranate …
Background Few data are available about the role of herbal extract loaded nanoparticles as
an alternative safe medicine for the management of a gastric ulcer. Aim This work is targeted …
an alternative safe medicine for the management of a gastric ulcer. Aim This work is targeted …