Cancer is a major public health problem worldwide with more than an estimated 19.3 million
new cases in 2020. The occurrence rises dramatically with age, and the overall risk …

Reggie-1/flotillin-2 and reggie-2/flotillin-1 are ubiquitously expressed, well-conserved
proteins that are associated with membrane microdomains known as rafts. Studies from us …

To comprehensively identify proteins interacting with 14-3-3ς in vivo, tandem affinity
purification and the multidimensional protein identification technology were combined to …

ARC92/ACID1 was identified as a novel specific target of the herpes simplex transactivator
VP16 using an affinity purification procedure. Characterization of the protein revealed tight …

PTOV1 is a mitogenic protein that shuttles between the nucleus and the cytoplasm in a cell
cycle-dependent manner. It consists of two homologous domains arranged in tandem that …

The proteins of flotillin-1 and flotillin-2 were originally discovered in axon regeneration of
goldfish retinal ganglion cells. They are generally used as marker proteins of lipid rafts and …

Flotillins are highly conserved proteins that localize into specific cholesterol rich
microdomains in cellular membranes. They have been shown to be associated with, for …

The AT-hook has been defined as a DNA binding peptide motif that contains a glycine-
arginine-proline (GRP) tripeptide core flanked by basic amino acids. Recent reports …

Flotillin-2 and flotillin-1, also called reggie-1 and reggie-2, are ubiquitously expressed and
highly conserved proteins. Originally, they were described as neuronal regeneration …

Background Prostate tumor over expressed gene 1 (PTOV1) has been reported as an
oncogene in several human cancers. However, the clinical significance and biological role …