Impact of predictive, preventive and precision medicine strategies in epilepsy

R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Inflammation, ictogenesis, and epileptogenesis: An exploration through human disease

THL Tan, P Perucca, TJ O'Brien, P Kwan, M Monif - Epilepsia, 2021 - Wiley Online Library
Epilepsy is seen historically as a disease of aberrant neuronal signaling manifesting as
seizures. With the discovery of numerous auto‐antibodies and the subsequent growth in …

Use and safety of immunotherapeutic management of N-methyl-d-aspartate receptor antibody encephalitis: a meta-analysis

M Nosadini, M Eyre, E Molteni, T Thomas… - JAMA …, 2021 - jamanetwork.com
Importance Overall, immunotherapy has been shown to improve outcomes and reduce
relapses in individuals withN-methyl-d-aspartate receptor (NMDAR) antibody encephalitis …

Systematic review of the clinical spectrum of CASPR2 antibody syndrome

M Boyko, KLK Au, C Casault, P de Robles… - Journal of Neurology, 2020 - Springer
Background Contactin-associated protein-like 2 (CASPR2) autoantibody disease has a
variable clinical phenotype. We present a case report and performed a systematic review of …

Anti-pan-neurofascin antibodies induce subclass-related complement activation and nodo-paranodal damage

L Appeltshauser, H Junghof, J Messinger, J Linke… - Brain, 2023 - academic.oup.com
Autoimmune neuropathy associated with antibodies against pan-neurofascin is a new
subtype of nodo-paranodopathy. It is relevant because it is associated with high morbidity …

Epidemiology of antibody-positive autoimmune encephalitis in Southwest China: a multicenter study

Y Gu, M Zhong, L He, W Li, Y Huang, J Liu… - Frontiers in …, 2019 - frontiersin.org
In recent years, as an increasing number of neuronal autoantibodies have been detected
and used for clinical diagnosis, clinicians have become more aware of autoimmune …

New-onset refractory status epilepticus (NORSE)

LM Ritter, L Nashef - Practical Neurology, 2021 - pn.bmj.com
New-onset refractory status epilepticus and its subcategory febrile infection-related epilepsy
syndrome are rare devastating clinical presentations in those without pre-existing relevant …

[HTML][HTML] The clinical features and prognosis of anti-NMDAR encephalitis depends on blood brain barrier integrity

Y Yu, Y Wu, X Cao, J Li, X Liao, J Wei… - Multiple sclerosis and …, 2021 - Elsevier
Abstract Background: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an
autoimmune nervous system disease that has become increasingly recognized. This …

The role of plasma exchange in the treatment of refractory autoimmune neurological diseases: a narrative review

S Jacob, G Mazibrada, SR Irani, A Jacob… - Journal of Neuroimmune …, 2021 - Springer
Autoimmune neurological disorders are commonly treated with immunosuppressive therapy.
In patients with refractory conditions, standard immunosuppression is often insufficient for …

Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis: a review

TY Zhang, MT Cai, Y Zheng, QL Lai, CH Shen… - Frontiers in …, 2021 - frontiersin.org
Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)
encephalitis, a rare subtype of autoimmune encephalitis, was first reported by Lai et al. The …