Thyroid hormones and cardiovascular disease

A Jabbar, A **itore, SHS Pearce, A Zaman… - Nature Reviews …, 2017 - nature.com
Myocardial and vascular endothelial tissues have receptors for thyroid hormones and are
sensitive to changes in the concentrations of circulating thyroid hormones. The importance …

Nongenomic actions of thyroid hormone

PJ Davis, F Goglia, JL Leonard - Nature Reviews Endocrinology, 2016 - nature.com
The nongenomic actions of thyroid hormone begin at receptors in the plasma membrane,
mitochondria or cytoplasm. These receptors can share structural homologies with nuclear …

Molecular aspects of thyroid hormone actions

SY Cheng, JL Leonard, PJ Davis - Endocrine reviews, 2010 - academic.oup.com
Cellular actions of thyroid hormone may be initiated within the cell nucleus, at the plasma
membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors …

Thyroid hormones and cancer: a comprehensive review of preclinical and clinical studies

E Krashin, A Piekiełko-Witkowska, M Ellis… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

Thyroid and cardiovascular disease: research agenda for enhancing knowledge, prevention, and treatment

AR Cappola, AS Desai, M Medici, LS Cooper, D Egan… - Circulation, 2019 - Am Heart Assoc
Thyroid hormones have long been known to have a range of effects on the cardiovascular
system. However, significant knowledge gaps exist concerning the precise molecular and …

Nanodrug delivery systems modulate tumor vessels to increase the enhanced permeability and retention effect

D Huang, L Sun, L Huang, Y Chen - Journal of personalized medicine, 2021 - mdpi.com
The use of nanomedicine for antitumor therapy has been extensively investigated for a long
time. Enhanced permeability and retention (EPR) effect-mediated drug delivery is currently …

Integrin αVβ3 Contains a Cell Surface Receptor Site for Thyroid Hormone that Is Linked to Activation of Mitogen-Activated Protein Kinase and Induction of …

JJ Bergh, HY Lin, L Lansing, SN Mohamed… - …, 2005 - academic.oup.com
Integrin αVβ3 is a heterodimeric plasma membrane protein whose several extracellular
matrix protein ligands contain an RGD recognition sequence. This study identifies integrin …

Mechanisms of nongenomic actions of thyroid hormone

PJ Davis, JL Leonard, FB Davis - Frontiers in neuroendocrinology, 2008 - Elsevier
The nongenomic actions of thyroid hormone require a plasma membrane receptor or
nuclear receptors located in cytoplasm. The plasma membrane receptor is located on …

Molecular functions of thyroid hormone signaling in regulation of cancer progression and anti-apoptosis

YC Liu, CT Yeh, KH Lin - International Journal of Molecular Sciences, 2019 - mdpi.com
Several physiological processes, including cellular growth, embryonic development,
differentiation, metabolism and proliferation, are modulated by genomic and nongenomic …

Emerging nanomedicines for early cancer detection and improved treatment: current perspective and future promise

DJ Bharali, SA Mousa - Pharmacology & therapeutics, 2010 - Elsevier
The application of nanotechnology to medicine, commonly referred to as 'nanomedicine',
has the potential to transform our approach to human health and disease. Research at the …