Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
Progress and achievements in glycosylation of flavonoids
In recent years, the chemistry of flavonoid glycosylation has undergone significant
developments. This mini-review is devoted to summarizing existing strategies and methods …
developments. This mini-review is devoted to summarizing existing strategies and methods …
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors
The underlying cause of many metabolic diseases is abnormal changes in enzyme activity
in metabolism. Inhibition of metabolic enzymes such as cholinesterases (ChEs; …
in metabolism. Inhibition of metabolic enzymes such as cholinesterases (ChEs; …
Synthesis and evaluation of 1, 3, 5-triaryl-2-pyrazoline derivatives as potent dual inhibitors of urease and α-glucosidase together with their cytotoxic, molecular …
In the present work, a concise library of 1, 3, 5-triaryl-2-pyrazolines (2a–2q) was designed
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
Identification of promising inhibitory heterocyclic compounds against acetylcholinesterase using QSAR, ADMET, biological activity, and molecular docking
Heterocyclic compounds exert diverse functions, especially acetylcholinesterase (AChE)
inhibition. Thus, identifying the association between their detailed structures and biological …
inhibition. Thus, identifying the association between their detailed structures and biological …
Design, synthesis, and structural characterization of thioflavones and thioflavonols as potential tyrosinase inhibitors: in vitro and in silico studies
To find new potential tyrosinase inhibitors, a diverse range of 2-arylchromone-4-thione
derivatives (2a–2p) were designed and synthesized by employing a multistep strategy, and …
derivatives (2a–2p) were designed and synthesized by employing a multistep strategy, and …
Design and synthesis of new flavonols as dual ɑ-amylase and ɑ-glucosidase inhibitors: structure-activity relationship, drug-likeness, in vitro and in silico studies
In this study, a library of new intriguing flavonol derivatives (1–17) was designed and
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
synthesized through a facile route involving Algar-Flynn-Oyamada reaction in a one-pot …
Synthesis and molecular docking studies of imines as α-glucosidase and α-amylase inhibitors
A Aispuro-Pérez, J López-Ávalos, F García-Páez… - Bioorganic …, 2020 - Elsevier
Imine functionality is found in many compounds with important biological activity. Thus, the
development of novel synthetic approaches for imines is important. In this work, it is propose …
development of novel synthetic approaches for imines is important. In this work, it is propose …
Synthetic flavonoids as potential antiviral agents against SARS-CoV-2 main protease
The COVID-19 pandemic has claimed more than a million lives worldwide within a short
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
Single-crystal X-ray structure, theoretical (Hirshfeld, electronic properties, NBO, NLO, RDG), and molecular docking studies of three phthalimidoethanesulfonamide …
Abstract The three N-substituted-2-phtalimidoethanesulfonamide derivatives, 2-(1, 3-
dioxoisoindolin-2-yl)-N-(2-isopropylphenyl) ethane-1-sulfonamide (I), N-(2, 6 …
dioxoisoindolin-2-yl)-N-(2-isopropylphenyl) ethane-1-sulfonamide (I), N-(2, 6 …