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Challenges and Prospects of DNA-Encoded Library Data Interpretation
DNA-encoded library (DEL) technology is a powerful platform for the efficient identification of
novel chemical matter in the early drug discovery process enabled by parallel screening of …
novel chemical matter in the early drug discovery process enabled by parallel screening of …
Visible light-enhancing antibacterial ability of gold ions for its application of the prevention and treatment of dentin caries
K Li, B **e, J Zhou, C Liang, C Liu, Y Qin, F Zhou… - Journal of Cleaner …, 2024 - Elsevier
To develop new antimicrobial strategy or agents has always been an eternal topic for the
researchers. In this study, we have found that the visible light can enhance the antibacterial …
researchers. In this study, we have found that the visible light can enhance the antibacterial …
Fluorescence-Based Simple and Practical Assay Method for DNA Damage Analysis in DNA-Encoded Library Synthesis
S Kang, GA Kim, MN Win, Y Ki, H Lee… - Bioconjugate …, 2024 - ACS Publications
The dsDNA-selective fluorescent-dye-based DNA damage assay was developed for DNA-
encoded library (DEL) synthesis. For the various DEL synthesis conditions, the assay was …
encoded library (DEL) synthesis. For the various DEL synthesis conditions, the assay was …
Optimization of Reaction Conditions for On‐DNA Synthesis of Ureas, Thioureas, and Sulfonamides
F Migliorini, A Ciamarone, D Neri… - Asian Journal of …, 2024 - Wiley Online Library
Isocyanates, isothiocyanates, and sulfonyl chlorides can be found in valuable building
blocks for the construction of DNA‐Encoded Chemical Libraries (DELs), leading to the …
blocks for the construction of DNA‐Encoded Chemical Libraries (DELs), leading to the …