Lab-on-chip for exosomes and microvesicles detection and characterization

MS Chiriacò, M Bianco, A Nigro, E Primiceri, F Ferrara… - Sensors, 2018 - mdpi.com
Interest in extracellular vesicles and in particular microvesicles and exosomes, which are
constitutively produced by cells, is on the rise for their huge potential as biomarkers in a high …

Recent advances in microfluidic platform for physical and immunological detection and capture of circulating tumor cells

MP Bhat, V Thendral, UT Uthappa, KH Lee, M Kigga… - Biosensors, 2022 - mdpi.com
CTCs (circulating tumor cells) are well-known for their use in clinical trials for tumor
diagnosis. Capturing and isolating these CTCs from whole blood samples has enormous …

Magnetic-based microfluidic device for on-chip isolation and detection of tumor-derived exosomes

H Xu, C Liao, P Zuo, Z Liu, BC Ye - Analytical chemistry, 2018 - ACS Publications
Exosomes are membrane-enclosed phospholipid extracellular vesicles, which can act as
mediators of intercellular communication. Although the original features endow tumor …

Electrochemical detection of circulating tumor cells based on DNA generated electrochemical current and rolling circle amplification

C Shen, S Liu, X Li, M Yang - Analytical Chemistry, 2019 - ACS Publications
Circulating tumor cells (CTCs) are important indicators for tumor diagnosis and tumor
metastasis. However, the extremely low levels of CTCs in peripheral blood challenges the …

Advances in isolation and detection of circulating tumor cells based on microfluidics

D Zou, D Cui - Cancer biology & medicine, 2018 - cancerbiomed.org
Circulating tumor cells (CTCs) are the cancer cells that circulate in the peripheral blood after
esca** from the original or metastatic tumors. CTCs could be used as non-invasive source …

Inner surface design of functional microchannels for microscale flow control

S Wang, X Yang, F Wu, L Min, X Chen, X Hou - Small, 2020 - Wiley Online Library
Fluidic flow behaviors in microfluidics are dominated by the interfaces created between the
fluids and the inner surface walls of microchannels. Microchannel inner surface designs …

Competitive electrochemical platform for ultrasensitive cytosensing of liver cancer cells by using nanotetrahedra structure with rolling circle amplification

D Sun, J Lu, Z Luo, L Zhang, P Liu, Z Chen - Biosensors and Bioelectronics, 2018 - Elsevier
In this work, a competitive and label-free electrochemical platform was performed for the
ultrasensitive cytosensing of liver cancer cells based on DNA nanotetrahedron (NTH) …

Recent advances in nano/microfluidics-based cell isolation techniques for cancer diagnosis and treatments

N Shanehband, SM Naghib - Biochimie, 2024 - Elsevier
Miniaturization has improved significantly in the recent decade, which has enabled the
development of numerous microfluidic systems. Microfluidic technologies have shown great …

[HTML][HTML] Nanotechnology-assisted isolation and analysis of circulating tumor cells on microfluidic devices

J Cheng, Y Liu, Y Zhao, L Zhang, L Zhang, H Mao… - Micromachines, 2020 - mdpi.com
Circulating tumor cells (CTCs), a type of cancer cell that spreads from primary tumors into
human peripheral blood and are considered as a new biomarker of cancer liquid biopsy. It …

A three-dimensional conductive scaffold microchip for effective capture and recovery of circulating tumor cells with high purity

SB Cheng, MM Chen, YK Wang, ZH Sun, Y Qin… - Analytical …, 2021 - ACS Publications
Effective acquirement of highly pure circulating tumor cells (CTCs) is very important for CTC-
related research. However, it is a great challenge since abundant white blood cells (WBCs) …