Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

B cells are crucial to the humoral immune response, originating in the bone marrow and
maturing in the spleen and lymph nodes. They primarily function to protect against a wide …

Background Primary membranous nephropathy (PMN) is an autoimmune glomerular
disease. IL-6 is a potential therapeutic target for PMN. Previous clinical studies have …

Background Primary membranous nephropathy (PMN) is usually caused by anti-
phospholipase A2 receptor (PLA2R) autoantibodies. There are different therapeutic options …

Background Primary membranous nephropathy (PMN) is a common cause of nephrotic
syndrome in adults. Forty percent of the patients continue to progress and eventually …

Background Primary membranous nephropathy (PMN) has a heterogeneous natural course.
Immunosuppressive therapy is recommended for PMN patients at moderate or high risk of …

Minimal Change Disease (MCD) is a predominant cause of idiopathic nephrotic syndrome in
the pediatric population, yet presents significant clinical challenges due to its frequent …

In recent years, the discovery of IL-12 family cytokines, which includes IL-12, IL-23, IL-27, IL-
35, and IL-39, whose biological functions directly or indirectly affect various autoimmune …

Membranous nephropathy (MN) occurs predominantly in middle-aged and elderly
individuals and ranks among the most prevalent etiologies of elderly nephrotic syndrome. As …

Objective This study aims to investigate the therapeutic effects of modified Huangqi Chifeng
decoction (MHCD) on proteinuria in membranous nephropathy (MN) and its potential …