Peripheral neuropathy is one of the most common side effects of chemotherapy, affecting up
to 60% of all cancer patients receiving chemotherapy. Moreover, paclitaxel induces …

Peripheral neuropathies are characterized by nerves damage and axonal loss, and they
could be classified in hereditary or acquired forms. Acquired peripheral neuropathies are …

Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Hepatocellular carcinoma (HCC) has become one of the major diseases that are threatening
human health in the 21st century. Currently there are many approaches to treat liver cancer …

Chronic pain resulting from nerve injury, tissue inflammation, and tumor invasion or
treatment, is a major health problem impacting the quality of life and producing a significant …

Vincristine (VCR), an alkaloid extracted from vinca, is often used in combination with other
chemotherapeutic drugs to treat a variety of cancers, such as acute lymphoblastic leukaemia …

Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …

Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common
malignancies. Paclitaxel and docetaxel are the most commonly used taxanes; however …

Background Paclitaxel is a widely prescribed chemotherapy drug for treating solid tumors.
However, paclitaxel-induced peripheral neuropathy (PIPN) is a common adverse effect …

Chemotherapy-induced neuropathic pain (CINP) is one of the most severe side effects of
anticancer agents, such as platinum-and taxanes-derived drugs (oxaliplatin, cisplatin …