Ultrafine-grained and heterostructured materials are currently of high interest due to their
superior mechanical and functional properties. Severe plastic deformation (SPD) is one of …

This article presents our take on the area of bulk ultrafine-grained materials produced by
severe plastic deformation (SPD). Over the last decades, research activities in this area have …

Osseointegration is a sophisticated bone and implant healing process comprising of initial
hematoma formation, immediate osteoimmunomodulation, angiogenesis, and osteogenesis …

With the need of rapid healing and long-term stability of dental implants, the existing Ti-
based implant materials do not meet completely the current expectation of patients. Low …

High-pressure torsion (HPT) refers to the processing of metals whereby samples are
subjected to a compressive force and concurrent torsional straining. Although the …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

Surface nanocrystallization is gaining increased attention due to its high potential of
enhancing mechanical functionality and modulating material's interaction with the …

Substrate grain structure and topography play major roles in mediating cell and bacteria
activities. Severe plastic deformation techniques, known as efficient metal-forming and grain …

Regenerative medicine is an emerging multidisciplinary field that aims to restore, maintain
or enhance tissues and hence organ functions. Regeneration of tissues can be achieved by …

Metallic materials, for example, stainless steel, titanium and its alloys, and tantalum, are
widely used for medical implants in trauma surgery, orthopedic and oral medicine.[1–3] …