Arterial tortuosity: novel implications for an old phenotype

S Ciurică, M Lopez-Sublet, BL Loeys, I Radhouani… - …, 2019 - Am Heart Assoc
The sites and patterns of tortuosity are dependent on key anatomic factors. These include:•
Anatomic fixation—vascular elongation between 2 fixed points will give rise to tortuosity. 16 …

Biologically-based mathematical modeling of tumor vasculature and angiogenesis via time-resolved imaging data

DA Hormuth, CM Phillips, C Wu, EABF Lima… - Cancers, 2021 - mdpi.com
Simple Summary The recruitment of new vasculature via angiogenesis is a critical
component of tumor development, which fundamentally influences tumor growth and …

3d multiparametric photoacoustic computed tomography of primary and metastatic tumors in living mice

J Kim, J Lee, S Choi, H Lee, J Yang, H Jeon, M Sung… - ACS …, 2024 - ACS Publications
Photoacoustic computed tomography (PACT), an emerging imaging modality in preclinical
cancer research, can provide multiparametric 3D information about structures, physiological …

Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy

AR Cantelmo, LC Conradi, A Brajic, J Goveia… - Cancer cell, 2016 - cell.com
Abnormal tumor vessels promote metastasis and impair chemotherapy. Hence, tumor vessel
normalization (TVN) is emerging as an anti-cancer treatment. Here, we show that tumor …

A brain tumor segmentation framework based on outlier detection

M Prastawa, E Bullitt, S Ho, G Gerig - Medical image analysis, 2004 - Elsevier
This paper describes a framework for automatic brain tumor segmentation from MR images.
The detection of edema is done simultaneously with tumor segmentation, as the knowledge …

Specific endothelial cells govern nanoparticle entry into solid tumors

BR Kingston, ZP Lin, B Ouyang, P MacMillan, J Ngai… - ACS …, 2021 - ACS Publications
The successful delivery of nanoparticles to solid tumors depends on their ability to pass
through blood vessels and into the tumor microenvironment. Here, we discovered a subset …

[HTML][HTML] 3-D ultrasound localization microscopy for identifying microvascular morphology features of tumor angiogenesis at a resolution beyond the diffraction limit of …

F Lin, SE Shelton, D Espíndola, JD Rojas, G Pinton… - Theranostics, 2017 - ncbi.nlm.nih.gov
Angiogenesis has been known as a hallmark of solid tumor cancers for decades, yet
ultrasound has been limited in its ability to detect the microvascular changes associated with …

A framework for geometric analysis of vascular structures: application to cerebral aneurysms

M Piccinelli, A Veneziani, DA Steinman… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
There is well-documented evidence that vascular geometry has a major impact in blood flow
dynamics and consequently in the development of vascular diseases, like atherosclerosis …

Cation-induced intramolecular coil-to-globule transition in poly (ADP-ribose)

T Wang, K Coshic, M Badiee, MR McDonald… - Nature …, 2024 - nature.com
Abstract Poly (ADP-ribose)(PAR), a non-canonical nucleic acid, is essential for DNA/RNA
metabolism and protein condensation, and its dysregulation is linked to cancer and …

Characterization of the 3-dimensional microstructure of a graphite negative electrode from a Li-ion battery

PR Shearing, LE Howard, PS Jørgensen… - Electrochemistry …, 2010 - Elsevier
The 3-dimensional microstructure of a porous electrode from a lithium-ion battery has been
characterized for the first time. We use X-ray tomography to reconstruct a 43× 348× 478μm …