Cancer is currently among the leading causes of mortality globally. Colorectal cancer (CRC)
ranks second among the most common types of cancer in terms of mortality worldwide. This …

Angiosarcoma is a highly malignancy of endothelial tumor and represents 1-2% of all soft
tissue sarcomas in humans. The aetiology of angiosarcoma is not clear but there are definite …

Despite rare cancers accounting for 25% of adult tumors, they are difficult to study due to the
low disease incidence and geographically dispersed patient populations, which has …

Synovial sarcoma (SS) is a rare and aggressive disease that accounts for 5%-10% of all soft
tissue sarcomas. Although it can occur at any age, it typically affects younger adults and …

The development of immune checkpoint inhibitors (ICI) marks an important breakthrough of
cancer therapies in the past years. However, only a limited fraction of patients benefit from …

Fluorescence in situ hybridization (FISH) is a standard technique used in routine diagnostics
of genetic aberrations. Thanks to simple FISH procedure is possible to recognize tumor …

Background Malignant tumors have become the most dangerous disease in recent years.
Chemotherapy is the most effective treatment for this disease; however, the problem of drug …

Liposarcoma, the most common soft tissue sarcoma, is a group of fat cell mesenchymal
tumors with different histological subtypes. The dysregulation of long non-coding RNAs …

Gynecologic sarcomas are uncommon neoplasms, the majority occurring in the uterus. Due
to the diverse nature of these, the description of “new” morphological types and the rarity of …

Transcriptional networks supervising class IIa HDAC expression are poorly defined. Here
we demonstrate that MEF2D is the key factor controlling HDAC9 transcription. This control …