Mental health consequences of traumatic brain injury

JR Howlett, LD Nelson, MB Stein - Biological psychiatry, 2022 - Elsevier
Traumatic brain injury (TBI) is associated with a host of psychiatric and neurobehavioral
problems. As mortality rates have declined for severe TBI, attention has turned to the …

Epidemiology of chronic effects of traumatic brain injury

J Haarbauer-Krupa, MJ Pugh, EM Prager… - Journal of …, 2021 - liebertpub.com
Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI,
recover from their symptoms within a few weeks, a small but meaningful subset experience …

[CARTE][B] The new psychology of health: Unlocking the social cure

C Haslam, J Jetten, T Cruwys, G Dingle, SA Haslam - 2018 - taylorfrancis.com
British Psychology Society Textbook of the Year 2020 Why do people who are more socially
connected live longer and have better health than those who are socially isolated? Why are …

A multidimensional approach to post-concussion symptoms in mild traumatic brain injury

S Polinder, MC Cnossen, RGL Real, A Covic… - Frontiers in …, 2018 - frontiersin.org
Mild traumatic brain injury (mTBI) presents a substantial burden to patients, families, and
health care systems. Whereas, recovery can be expected in the majority of patients, a subset …

Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes

N Hegdekar, C Sarkar, S Bustos, RM Ritzel… - Autophagy, 2023 - Taylor & Francis
Excessive and prolonged neuroinflammation following traumatic brain injury (TBI)
contributes to long-term tissue damage and poor functional outcomes. However, the …

Microglial depletion with CSF1R inhibitor during chronic phase of experimental traumatic brain injury reduces neurodegeneration and neurological deficits

RJ Henry, RM Ritzel, JP Barrett, SJ Doran… - Journal of …, 2020 - jneurosci.org
Chronic neuroinflammation with sustained microglial activation occurs following severe
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …

Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI study

MB Stein, S Jain, JT Giacino, H Levin, S Dikmen… - JAMA …, 2019 - jamanetwork.com
Importance Traumatic brain injury (TBI) has been associated with adverse mental health
outcomes, such as posttraumatic stress disorder (PTSD) and major depressive disorder …

Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis

DC Perry, VE Sturm, MJ Peterson, CF Pieper… - Journal of …, 2016 - thejns.org
OBJECT Mild traumatic brain injury (TBI) has been proposed as a risk factor for the
development of Alzheimer's disease, Parkinson's disease, depression, and other illnesses …

The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …