Open source software for the analysis of microarray data

S Dudoit, RC Gentleman, J Quackenbush - Biotechniques, 2003 - Taylor & Francis
DNA microarray assays represent the first widely used application that attempts to build
upon the information provided by genome projects in the study of biological questions. One …

Summaries of Affymetrix GeneChip probe level data

RA Irizarry, BM Bolstad, F Collin, LM Cope… - Nucleic acids …, 2003 - academic.oup.com
High density oligonucleotide array technology is widely used in many areas of biomedical
research for quantitative and highly parallel measurements of gene expression. Affymetrix …

A model-based background adjustment for oligonucleotide expression arrays

Z Wu, RA Irizarry, R Gentleman… - Journal of the …, 2004 - Taylor & Francis
High-density oligonucleotide expression arrays are widely used in many areas of
biomedical research. Affymetrix GeneChip arrays are the most popular. In the Affymetrix …

The local and systemic inflammatory transcriptome after acute kidney injury

DN Grigoryev, M Liu, HT Hassoun… - Journal of the …, 2008 - journals.lww.com
Studies in humans and animal models have demonstrated that acute kidney injury (AKI) has
a significant effect on the function of extrarenal organs. The combination of AKI and lung …

[หนังสือ][B] Statistics for microarrays: design, analysis and inference

E Wit, J McClure - 2004 - books.google.com
Interest in microarrays has increased considerably in the last ten years. This increase in the
use of microarray technology has led to the need for good standards of microarray …

Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy

HT Hassoun, DN Grigoryev, ML Lie… - American Journal …, 2007 - journals.physiology.org
Acute kidney injury (AKI) is associated with significant mortality, which increases further
when combined with acute lung injury. Experiments in rodents have shown that kidney …

Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice

J Li, DN Grigoryev, SQ Ye, L Thorne… - Journal of Applied …, 2005 - journals.physiology.org
Obstructive sleep apnea (OSA), a condition tightly linked to obesity, leads to chronic
intermittent hypoxia (CIH) during sleep. There is emerging evidence that OSA is …

Stochastic models inspired by hybridization theory for short oligonucleotide arrays

Z Wu, RA Irizarry - Proceedings of the eighth annual international …, 2004 - dl.acm.org
High density oligonucleotide expression arrays are a widely used tool for the measurement
of gene expression on a large scale. Affymetrix GeneChip arrays appear to dominate this …

Neutrophil gelatinase–associated lipocalin mediates 13-cis retinoic acid–induced apoptosis of human sebaceous gland cells

AM Nelson, W Zhao, KL Gilliland, AL Zaenglein… - The Journal of clinical …, 2008 - jci.org
13-cis retinoic acid (13-cis RA; also known as isotretinoin) is the most potent agent available
for treatment of acne. It is known that the drug induces apoptosis in cells cultured from …

PFT1, the MED25 subunit of the plant Mediator complex, promotes flowering through CONSTANS dependent and independent mechanisms in Arabidopsis

S Iñigo, MJ Alvarez, B Strasser, A Califano… - The Plant …, 2012 - Wiley Online Library
Two aspects of light are very important for plant development: the length of the light phase or
photoperiod and the quality of incoming light. Photoperiod detection allows plants to …