The airway epithelium comprises of different cell types and acts as a physical barrier
preventing pathogens, including inhaled particles and microbes, from entering the lungs …

Autophagy plays a critical role in maintaining cellular homeostasis and responding to
various stress conditions by the degradation of intracellular components. In this narrative …

Mitochondrial biology has seen a surge in popularity in the past 5 years, with the emergence
of numerous new avenues of exciting mitochondria-related research including …

Deep learning is a promising tool that uses nonlinear transformations to extract features from
high-dimensional data. Deep learning is challenging in genome-wide association studies …

Autophagy (or macroautophagy) is a key cellular process that removes damaged molecules
(particularly proteins) and subcellular organelles to maintain cellular homeostasis. There is …

Exposure of the airways epithelium to environmental insults, including cigarette smoke,
results in increased oxidative stress due to unbalance between oxidants and antioxidants in …

Autophagy is an evolutionarily conserved cellular system crucial for cellular homeostasis
that protects cells from a broad range of internal and extracellular stresses. Autophagy …

Autophagy is the key process by which the cell degrades parts of itself within the lysosomes.
It maintains cell survival and homeostasis by removing molecules (particularly proteins) …

Cigarette smoke impairs autophagy, an intracellular protein degradation system, but the
consequences of this defect have not been fully elucidated, especially in macrophages …

The preservation of cellular homeostasis requires the synthesis of new proteins
(proteostasis) and organelles, and the effective removal of misfolded or impaired proteins …