Next-generation sequencing (NGS) is present in all fields of life science, which has greatly
promoted the development of basic research while being gradually applied in clinical …

With digital transformation and the general application of new technologies, data storage is
facing new challenges with the demand for high-density loading of massive information. In …

Whole genome amplification (WGA) is a technology for non‐selective amplification of the
whole genome sequence, first appearing in 1992. Its primary purpose is to amplify and …

The toxicity evaluation system of environmental pollutants has undergone numerous
changes due to the application of new technologies. Single-cell toxicogenomics is rapidly …

The field of single-cell analysis has advanced rapidly in the last decade and is providing
new insights into the characterization of intercellular genetic heterogeneity and complexity …

Motivation Multiple displacement amplification (MDA) has become the most commonly used
method of whole genome amplification, generating a vast amount of DNA with higher …

High-quality whole-genome amplification (WGA) of individual cells is the primary step for
characterizing the genetic information on single cells in biology and medicine. As the most …

Multiple displacement amplification (MDA) based on isothermal random priming and high
fidelity phi29 DNA polymerase-mediated processive extension has revolutionized the field of …

Transcriptome sequencing has emerged as an important research tool for exploring the
mysteries of life at the single-cell level. However, its wide application is limited by the bias …

Background The extremely small amount of DNA in a cell makes it difficult to study the whole
genome of single cells, so whole‐genome amplification (WGA) is necessary to increase the …