The immunopathogenesis of Alzheimer's disease is related to the composition of gut microbiota

F Leblhuber, D Ehrlich, K Steiner, S Geisler, D Fuchs… - Nutrients, 2021 - mdpi.com
The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …

Novel chemical and biological insights of inositol derivatives in Mediterranean plants

L Siracusa, E Napoli, G Ruberto - Molecules, 2022 - mdpi.com
Inositols (Ins) are natural compounds largely widespread in plants and animals. Bio-
sinthetically they derive from sugars, possessing a molecular structure very similar to the …

Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption

C Wu, F Yang, H Zhong, J Hong, H Lin, M Zong… - Cell Host & Microbe, 2024 - cell.com
Numerous studies have reported critical roles for the gut microbiota in obesity. However, the
specific microbes that causally contribute to obesity and the underlying mechanisms remain …

[HTML][HTML] Inositols depletion and resistance: Principal mechanisms and therapeutic strategies

E Lepore, R Lauretta, M Bianchini… - International Journal of …, 2021 - mdpi.com
Inositols are natural molecules involved in several biochemical and metabolic functions in
different organs and tissues. The term “inositols” refers to five natural stereoisomers, among …

Neurobiology and applications of inositol in psychiatry: a narrative review

C Concerto, C Chiarenza, A Di Francesco… - Current issues in …, 2023 - mdpi.com
Inositol is a natural sugar-like compound, commonly present in many plants and foods. It is
involved in several biochemical pathways, most of them controlling vital cellular …

Gas chromatography/mass spectrometry-based metabolite profiling of coffee beans obtained from different altitudes and origins with various postharvest processing

F Amalia, P Aditiawati, Yusianto, SP Putri, E Fukusaki - Metabolomics, 2021 - Springer
Introduction Coffee is a popular beverage because of its pleasant aroma and distinctive
flavor. The flavor of coffee results from chemical transformations influenced by various …

[HTML][HTML] Inositol and non-alcoholic fatty liver disease: A systematic review on deficiencies and supplementation

A Pani, R Giossi, D Menichelli, VA Fittipaldo, F Agnelli… - Nutrients, 2020 - mdpi.com
Liver lipid accumulation is a hallmark of non-alcoholic fatty liver disease (NAFLD), broadly
associated with insulin resistance. Inositols (INS) are ubiquitous polyols implied in many …

[HTML][HTML] Myoinositols prevent gestational diabetes mellitus and related complications: a systematic review and meta-analysis of randomized controlled trials

D Greff, S Vancsa, A Varadi, J Szinte, S Park, P Hegyi… - Nutrients, 2023 - mdpi.com
Although gestational diabetes mellitus (GDM) has several short-and long-term adverse
effects on the mother and the offspring, no medicine is generally prescribed to prevent GDM …

Metabolism responses in the intestine of Oreochromis mossambicus exposed to salinity, alkalinity and salt-alkalinity stress using LC-MS/MS-based metabolomics

H Su, Y Li, D Ma, J Fan, Z Zhong, H Zhu - Comparative Biochemistry and …, 2023 - Elsevier
Multiple abiotic stresses are imposed on fish as a result of unprecedented changes in
temperature and precipitation patterns in recent decades. It is unclear how teleosts respond …

Dietary inositol improved glucose and lipid metabolism mediated by the Insulin-PI3K-Akt signaling pathway in Pacific white shrimp (Litopenaeus vannamei)

J Lu, X Tao, M Li, X Zhang, Q Zhou, J Luo, T Zhu, L Jiao… - Aquaculture, 2023 - Elsevier
The present study aimed to evaluate the effects of dietary inositol level (0.86, 1.34, 1.40,
2.30, 3.88 and 7.50 g kg− 1) on glucose and lipid homeostasis in Litopenaeus vannamei …