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A census of human RNA-binding proteins
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …
[HTML][HTML] MicroRNAs and spermatogenesis
N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
Global RNA recognition patterns of post‐transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo
The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …
Protein–DNA/RNA interactions: an overview of investigation methods in the-omics era
F Cozzolino, I Iacobucci, V Monaco… - Journal of Proteome …, 2021 - ACS Publications
The fields of application of functional proteomics are not limited to the study of protein–
protein interactions; they also extend to those involving protein complexes that bind DNA or …
protein interactions; they also extend to those involving protein complexes that bind DNA or …
Post-transcriptional regulation of anti-apoptotic BCL2 family members
Anti-apoptotic B cell lymphoma 2 (BCL2) family members (BCL2, MCL1, BCLxL, BCLW, and
BFL1) are key players in the regulation of intrinsic apoptosis. Dysregulation of these proteins …
BFL1) are key players in the regulation of intrinsic apoptosis. Dysregulation of these proteins …
Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease
RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …
POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins
Abstract We present POSTAR (http://POSTAR. ncrnalab. org), a resource of POST-tr A
nscriptional R egulation coordinated by RNA-binding proteins (RBPs). Precise …
nscriptional R egulation coordinated by RNA-binding proteins (RBPs). Precise …
[HTML][HTML] The most common technologies and tools for functional genome analysis
E Gasperskaja, V Kučinskas - Acta Medica Lituanica, 2017 - ncbi.nlm.nih.gov
Since the sequence of the human genome is complete, the main issue is how to understand
the information written in the DNA sequence. Despite numerous genome-wide studies that …
the information written in the DNA sequence. Despite numerous genome-wide studies that …
Germ granule-mediated RNA regulation in male germ cells
T Lehtiniemi, N Kotaja - Reproduction, 2018 - rep.bioscientifica.com
Germ cells have exceptionally diverse transcriptomes. Furthermore, the progress of
spermatogenesis is accompanied by dramatic changes in gene expression patterns, the …
spermatogenesis is accompanied by dramatic changes in gene expression patterns, the …
Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution
N Jain, HC Lin, CE Morgan… - Proceedings of the …, 2017 - National Acad Sciences
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a multipurpose RNA-binding
protein (RBP) involved in normal and pathological RNA metabolism. Transcriptome-wide …
protein (RBP) involved in normal and pathological RNA metabolism. Transcriptome-wide …