A census of human RNA-binding proteins

S Gerstberger, M Hafner, T Tuschl - Nature Reviews Genetics, 2014 - nature.com
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …

[HTML][HTML] MicroRNAs and spermatogenesis

N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

Global RNA recognition patterns of post‐transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo

E Holmqvist, PR Wright, L Li, T Bischler… - The EMBO …, 2016 - embopress.org
The molecular roles of many RNA‐binding proteins in bacterial post‐transcriptional gene
regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA …

Protein–DNA/RNA interactions: an overview of investigation methods in the-omics era

F Cozzolino, I Iacobucci, V Monaco… - Journal of Proteome …, 2021 - ACS Publications
The fields of application of functional proteomics are not limited to the study of protein–
protein interactions; they also extend to those involving protein complexes that bind DNA or …

Post-transcriptional regulation of anti-apoptotic BCL2 family members

J Cui, WJ Placzek - International journal of molecular sciences, 2018 - mdpi.com
Anti-apoptotic B cell lymphoma 2 (BCL2) family members (BCL2, MCL1, BCLxL, BCLW, and
BFL1) are key players in the regulation of intrinsic apoptosis. Dysregulation of these proteins …

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease

S Gerstberger, M Hafner, M Ascano… - Systems biology of RNA …, 2014 - Springer
RNA-binding proteins (RBPs) are effectors and regulators of posttranscriptional gene
regulation (PTGR). RBPs regulate stability, maturation, and turnover of all RNAs, often …

POSTAR: a platform for exploring post-transcriptional regulation coordinated by RNA-binding proteins

B Hu, YCT Yang, Y Huang, Y Zhu… - Nucleic acids research, 2017 - academic.oup.com
Abstract We present POSTAR (http://POSTAR. ncrnalab. org), a resource of POST-tr A
nscriptional R egulation coordinated by RNA-binding proteins (RBPs). Precise …

[HTML][HTML] The most common technologies and tools for functional genome analysis

E Gasperskaja, V Kučinskas - Acta Medica Lituanica, 2017 - ncbi.nlm.nih.gov
Since the sequence of the human genome is complete, the main issue is how to understand
the information written in the DNA sequence. Despite numerous genome-wide studies that …

Germ granule-mediated RNA regulation in male germ cells

T Lehtiniemi, N Kotaja - Reproduction, 2018 - rep.bioscientifica.com
Germ cells have exceptionally diverse transcriptomes. Furthermore, the progress of
spermatogenesis is accompanied by dramatic changes in gene expression patterns, the …

Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

N Jain, HC Lin, CE Morgan… - Proceedings of the …, 2017 - National Acad Sciences
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a multipurpose RNA-binding
protein (RBP) involved in normal and pathological RNA metabolism. Transcriptome-wide …