Both a leaky gut (a barrier defect of the intestinal surface) and gut dysbiosis (a change in the
intestinal microbial population) are intrinsic to sepsis. While sepsis itself can cause …

Over the past decade it has become clear that various aspects of host physiology,
metabolism, and immunity are intimately associated with the microbiome and its interactions …

Objective To profile the gut microbiome (GM) in infants with congenital heart disease (CHD)
undergoing cardiac surgery compared with matched infants and to investigate the …

Importance Detection ofClostridioides difficilehas frequently been described in
asymptomatic infants and children, but accurate estimates across the age spectrum are …

The Karius test is a commercially available metagenomic next-generation sequencing test
that can identify cell-free microbial DNA from over 1,200 pathogens. Although study designs …

Postoperative complications are a major problem occurring in up to 50% of patients
undergoing major abdominal surgery. Occurrence of postoperative complications is …

Aim. Sickle cell disease has witnessed a 41.4% surge from 2000 to 2021, significantly
affecting morbidity and mortality rates, particularly in children from regions with elevated …

A high level of β-amyloid (Aβ) in the brains of patients with Alzheimer's disease (AD)
generates reactive oxygen species that induce neuronal death and DNA damage. The …

Clostridioides difficile infection (CDI) is responsible for around 300,000 hospitalizations
yearly in the United States, with the associated monetary cost being billions of dollars. Gut …

Materials and Methods: The study included 34 children and young adolescents with SCD
and 41 healthy volunteer participants. The microbiome was assessed by 16S rRNA …