Cutaneous leishmaniasis: updates in diagnosis and management

NE Aronson, CA Joya - Infectious Disease Clinics, 2019 - id.theclinics.com
Cutaneous leishmaniasis (CL) is a severely neglected tropical disease that has been
significantly increasing in numbers affected over the past decades, with a change in global …

Tackling drug resistance and other causes of treatment failure in leishmaniasis

GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …

Leishmaniasis immunopathology—impact on design and use of vaccines, diagnostics and drugs

PM Kaye, I Cruz, A Picado, K Van Bocxlaer… - Seminars in …, 2020 - Springer
Leishmaniasis is a disease complex caused by 20 species of protozoan parasites belonging
to the genus Leishmania. In humans, it has two main clinical forms, visceral leishmaniasis …

American tegumentary leishmaniasis in Brazil: a critical review of the current therapeutic approach with systemic meglumine antimoniate and short‐term possibilities …

SH Carvalho, F Frézard, NP Pereira… - Tropical Medicine & …, 2019 - Wiley Online Library
Abstract Objectives Meglumine antimoniate (MA; Glucantime®), the 80‐year‐old first‐line
systemic treatment for all forms of American tegumentary leishmaniasis (ATL) caused by …

Mutual role of patients and the healthcare system in the control of cutaneous leishmaniasis

M Bamorovat, I Sharifi… - Transboundary and …, 2023 - Wiley Online Library
Leishmaniasis is a neglected and old emerging/reemerging disease that has extremely
increased and expanded in the different geographical areas. Cutaneous leishmaniasis (CL) …

Efficacy and tolerability of miltefosine in the treatment of cutaneous leishmaniasis

JAM Ware, EM O'Connell, T Brown… - Clinical Infectious …, 2021 - academic.oup.com
Background Cutaneous leishmaniasis (CL) is a neglected tropical disease causing an
estimated 1 million new cases annually. While antimonial compounds are the standard of …

Natural resistance to meglumine antimoniate is associated with treatment failure in cutaneous leishmaniasis caused by Leishmania (Viannia) panamensis

OL Fernández, M Rosales-Chilama… - PLOS Neglected …, 2024 - journals.plos.org
The multifactorial basis of therapeutic response can obscure the relation between
antimicrobial drug susceptibility and clinical outcome. To discern the relationship between …

Miltefosine for the treatment of cutaneous leishmaniasis—A pilot study from Ethiopia

S van Henten, AB Tesfaye, SG Abdela… - PLoS neglected …, 2021 - journals.plos.org
Background Cutaneous leishmaniasis (CL) in Ethiopia, caused by Leishmania aethiopica, is
often severe and hard to treat compared to CL caused by other species elsewhere …

Cutaneous leishmaniasis treatment and therapeutic outcomes in special populations: A collaborative retrospective study

MDM Castro, J Rode, PRL Machado… - PLoS neglected …, 2023 - journals.plos.org
Background Treatment guidance for children and older adult patients affected by cutaneous
leishmaniasis (CL) is unclear due to limited representation of these groups in clinical trials …

Systematic review of treatment failure and clinical relapses in leishmaniasis from a multifactorial perspective: Clinical aspects, factors associated with the parasite and …

GA Santos, JM Sousa, AHBM Aguiar… - Tropical Medicine and …, 2023 - mdpi.com
Leishmaniasis is a disease caused by protozoa of the genus Leishmania. Treatment options
are limited, and there are frequent cases of treatment failure and clinical relapse. To …