Periodontal diseases

DF Kinane, PG Stathopoulou… - Nature reviews Disease …, 2017 - nature.com
Periodontal diseases comprise a wide range of inflammatory conditions that affect the
supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could …

Host genetics role in the pathogenesis of periodontal disease and caries

L Nibali, A Di Iorio, YK Tu… - Journal of clinical …, 2017 - Wiley Online Library
Background This study aimed to produce the latest summary of the evidence for association
of host genetic variants contributing to both periodontal diseases and caries. Materials and …

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

M Munz, C Willenborg, GM Richter… - Human molecular …, 2017 - academic.oup.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. The disease is …

Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci

M Munz, GM Richter, BG Loos, S Jepsen… - European Journal of …, 2019 - nature.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. It is classified into the …

Subgingival microbiome and clinical periodontal status in an elderly cohort: The WHICAP ancillary study of oral health

PN Papapanou, H Park, B Cheng… - Journal of …, 2020 - Wiley Online Library
Background There is a sparsity of data describing the periodontal microbiome in elderly
individuals. We analyzed the association of subgingival bacterial profiles and clinical …

[HTML][HTML] An evidence-based update on the molecular mechanisms underlying periodontal diseases

SSB Qasim, D Al-Otaibi, R Al-Jasser, SS Gul… - International journal of …, 2020 - mdpi.com
Several investigators have reported about the intricate molecular mechanism underlying
periodontal diseases (PD). Nevertheless, the role of specific genes, cells, or cellular …

[HTML][HTML] Next-generation examination, diagnosis, and personalized medicine in periodontal disease

T Kikuchi, J Hayashi, A Mitani - Journal of personalized medicine, 2022 - mdpi.com
Periodontal disease, a major cause of tooth loss, is an infectious disease caused by bacteria
with the additional aspect of being a noncommunicable disease closely related to lifestyle …

Diagnostic and prognostic ability of salivary MMP‐9 and S100A8 for periodontitis

HD Kim, S Kim, S Jeon, SJ Kim… - Journal of Clinical …, 2020 - Wiley Online Library
Objectives Salivary diagnostic using matrix metalloproteinase (MMP) and S100 for
periodontitis is a promising issue. However, its prognostic effect is still unclear. This study …

Genetics of periodontitis: discovery, biology, and clinical impact

AS Schaefer - Periodontology 2000, 2018 - Wiley Online Library
This review provides an update on genome‐wide association studies in periodontitis.
Studies in populations with European ancestry have dominated the landscape of …

[HTML][HTML] Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study

S Bell, JT Gibson, EL Harshfield, HS Markus - Atherosclerosis, 2020 - Elsevier
Background and aims Observational studies have reported an association between
periodontitis and cardiovascular disease but whether this association is causal is uncertain …