According to current concepts of white analytical chemistry (WAC), the use of organic
solvents those are teratogenic and carcinogenic must be avoided for the protection of the …

Background Azilsartan medoxomil (AZL) is an anti-hypertensive drug, and its numerous
FDCs are used for the treatment of hypertension. Numerous chromatographic methods have …

The present study focuses on optimizing, develo**, and validating a sensitive and specific
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …

Chlorthalidone (CHL) is an anti-hypertensive that reduces active sodium reabsorption and
peripheral vascular resistance. Also, it is a diuretic commonly known as a thiazide diuretic …

Background Numerous fixed-dose combinations (FDCs) of cilnidipine (CIL) with
chlorthalidone (CLT) and azilsartan medoxomil (AZL) are used for the treatment of …

Hypertension is the most prominent disease found in people due to stressful routines and
the working environment. The fixed-dose combination (FDC) of azilsartan medoxomil (AZL) …

Background: Products with multiple active substances mixed in a single dosage form are
fixed-dose combinations. These are justified for a variety of reasons. These include a) …

A new combination of metoprolol succinate, telmisartan, and cilnidipine is recently approved
to treat hypertension effectively. A reversed‐phase liquid chromatography method was …

This work describes a chromatographic technique for quantifying azilsartan medoxomil
(AZL) and cilnidipine (CIL) in bulk and pharmaceutical formulations using quality by design …

According to the green chemistry approach, the usage of carcinogenic and teratogenic
organic solvents should be minimized in the development of the analytical method for the …