Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite arbors, and dendritic …

Notch signaling induced by canonical Notch ligands is critical for normal embryonic
development and tissue homeostasis through the regulation of a variety of cell fate decisions …

Lymphoid follicles are B-cell-rich compartments of lymphoid organs that function as sites of
B-cell antigen encounter and differentiation. CXC chemokine receptor-5 (CXCR5) is …

In vertebrates, Notch signaling is generally thought to inhibit neural differentiation. However,
whether Notch can also promote specific early cell fates in this context is unknown. We …

The Notch signaling pathway regulates a diverse array of cell types and cellular processes
and is tightly regulated by ligand binding. Both canonical and noncanonical Notch ligands …

The Notch pathway is prominent among those known to regulate neural development in
vertebrates. Notch receptor activation can inhibit neurogenesis, maintain neural progenitor …

The Notch pathway, although originally identified in fruit flies, is now among the most heavily
studied in mammalian biology. In mice, loss-of-function and gain-of-function work has …

▪ Abstract Intensive studies of three proteins—Presenilin, Notch, and the amyloid precursor
protein (APP)—have led to the recognition of a direct intersection between early …

Proper growth and branching of dendrites are crucial for nervous system function; patterns of
dendritic arborization determine the nature and amount of innervation that a neuron receives …

Notch receptors in a given cell are activated by cell surface ligands in neighbouring cells but
can also be inhibited by the ligands present within the same cell. This process is known as …