Quantitative magnetic resonance imaging of brain anatomy and in vivo histology
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …
aims primarily at local image contrast. It provides specific physical parameters related to the …
Using high-resolution quantitative map** of R1 as an index of cortical myelination
A fundamental tenet of neuroscience is that cortical functional differentiation is related to the
cross-areal differences in cyto-, receptor-, and myeloarchitectonics that are observed in ex …
cross-areal differences in cyto-, receptor-, and myeloarchitectonics that are observed in ex …
[HTML][HTML] hMRI–A toolbox for quantitative MRI in neuroscience and clinical research
Neuroscience and clinical researchers are increasingly interested in quantitative magnetic
resonance imaging (qMRI) due to its sensitivity to micro-structural properties of brain tissue …
resonance imaging (qMRI) due to its sensitivity to micro-structural properties of brain tissue …
Quantitative multi-parameter map** of R1, PD*, MT, and R2* at 3T: a multi-center validation
Multi-center studies using magnetic resonance imaging facilitate studying small effect sizes,
global population variance and rare diseases. The reliability and sensitivity of these multi …
global population variance and rare diseases. The reliability and sensitivity of these multi …
GnRH replacement rescues cognition in Down syndrome
M Manfredi-Lozano, V Leysen, M Adamo, I Paiva… - Science, 2022 - science.org
At the present time, no viable treatment exists for cognitive and olfactory deficits in Down
syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive …
syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive …
[HTML][HTML] Unified segmentation based correction of R1 brain maps for RF transmit field inhomogeneities (UNICORT)
Quantitative map** of the longitudinal relaxation rate (R1= 1/T1) in the human brain
enables the investigation of tissue microstructure and macroscopic morphology which are …
enables the investigation of tissue microstructure and macroscopic morphology which are …
[HTML][HTML] Widespread age-related differences in the human brain microstructure revealed by quantitative magnetic resonance imaging
A pressing need exists to disentangle age-related changes from pathologic
neurodegeneration. This study aims to characterize the spatial pattern and age-related …
neurodegeneration. This study aims to characterize the spatial pattern and age-related …
On the accuracy of T1 map**: Searching for common ground
Purpose There are many T1 map** methods available, each of them validated in
phantoms and reporting excellent agreement with literature. However, values in literature …
phantoms and reporting excellent agreement with literature. However, values in literature …
[HTML][HTML] Structural covariance networks are coupled to expression of genes enriched in supragranular layers of the human cortex
Complex network topology is characteristic of many biological systems, including anatomical
and functional brain networks (connectomes). Here, we first constructed a structural …
and functional brain networks (connectomes). Here, we first constructed a structural …
Advances in MRI-based computational neuroanatomy: from morphometry to in-vivo histology
Non-invasive brain tissue characterization using qMRI or hMRI has significant implications
for both research and clinics. Both approaches improve comparability across sites and time …
for both research and clinics. Both approaches improve comparability across sites and time …