Cancer stem cells (CSCs) play a central role in the development of cancer. The canonical
Wnt/β-catenin pathway is critical for maintaining stemness of CSCs. Phytochemicals from …

Cancer stem cells are responsible for tumorigenesis, progression, recurrence and
metastasis. Intestinal stem cells (ISCs) are regarded as the origin of intestinal neoplasia …

A multiple colorimetric assay has been introduced to evaluate the proliferation and
determination of survival fraction (SF) of irradiated cells. The estimation of SF based on the …

Drug screening is currently demanding for realistic models that are able to reproduce the
structural features of solid tumors. 3D cell culture systems, namely spheroids, emerged as a …

Retinoblastoma (RB) is a primary intraocular malignancy in childhood, and may develop
relapse and metastatic disease. This study was to identify the stem-cell properties of primary …

Purpose High-linear energy transfer (high LET) irradiation has significant cytotoxic effects on
different cancerous stem-like cells (CSLCs) such as colorectal CSLCs. A review of the …

Background: Electroporation has become a routine technique for rapid drug delivery for the
treatment of cancer. Because of its simplicity and wide range of application, it has been …

Background: Ionizing radiation is present in all environment of the Earth's surface, beneath
the Earth and in the atmosphere. Human beings are exposed to external radiation from their …

Treatment modalities can reduce cancer-related mortality; however, a majority of patients
develop drug resistance, metastasis and relapse. It has been proposed that tumorigenic …

Collagen is an abundant structural protein in the extracellular matrix and plays a role in both
structural integrity and support that guides tissue formation and homeostasis. Collagen or …