A gene expression signature‐based nomogram model in prediction of breast cancer bone metastases

C Zhao, Y Lou, Y Wang, D Wang, L Tang… - Cancer …, 2019 - Wiley Online Library
Breast cancer is prone to form bone metastases and subsequent skeletal‐related events
(SREs) dramatically decrease patients' quality of life and survival. Prediction and early …

A Network‐Constrain Weibull AFT Model for Biomarkers Discovery

C Angelini, D De Canditiis, I De Feis… - Biometrical …, 2024 - Wiley Online Library
We propose AFTNet, a novel network‐constraint survival analysis method based on the
Weibull accelerated failure time (AFT) model solved by a penalized likelihood approach for …

Machine learning methods for survival analysis with clinical and transcriptomics data of breast cancer

LMT Doan, C Angione, A Occhipinti - Computational biology and machine …, 2022 - Springer
Breast cancer is one of the most common cancers in women worldwide, which causes an
enormous number of deaths annually. However, early diagnosis of breast cancer can …

A new biomarker panel of ultraconserved long non-coding RNAs for bladder cancer prognosis by a machine learning based methodology

A Ciaramella, E Di Nardo, D Terracciano, L Conte… - BMC …, 2022 - Springer
Background Recent studies have indicated that a special class of long non-coding RNAs
(lncRNAs), namely Transcribed-Ultraconservative Regions are transcribed from specific …

Cosmonet: An r package for survival analysis using screening-network methods

A Iuliano, A Occhipinti, C Angelini, I De Feis, P Liò - Mathematics, 2021 - mdpi.com
Identifying relevant genomic features that can act as prognostic markers for building
predictive survival models is one of the central themes in medical research, affecting the …

Nomogram models based on the gene expression in prediction of breast cancer bone metastasis

T Fan, D Bei, S Li - Journal of Healthcare Engineering, 2022 - Wiley Online Library
Objective. The aim of this study is to design a weighted co‐expression network and build
gene expression signature‐based nomogram (GESBN) models for predicting the likelihood …

A Practical Guide to Integrating Multimodal Machine Learning and Metabolic Modeling

S Vijayakumar, G Magazzù, P Moon… - … Systems Biology in …, 2022 - Springer
Complex, distributed, and dynamic sets of clinical biomedical data are collectively referred to
as multimodal clinical data. In order to accommodate the volume and heterogeneity of such …

Computational logic for biomedicine and neurosciences

E De Maria, J Despeyroux, A Felty, P Lió… - … to Modeling and …, 2023 - books.google.com
188 Symbolic Approaches to Modeling and Analysis of Biological Systems properties. In
biomedicine, the study of multi-omic pathway interactions, together with clinical and …

A logical framework for modelling breast cancer progression

J Despeyroux, A Felty, P Lio, C Olarte - Molecular Logic and …, 2019 - Springer
Data streams for a personalised breast cancer programme could include collections of
image data, tumour genome sequencing, likely at the single cell level, and liquid biopsies …

Gene Screening in High-Throughput Right-Censored Lung Cancer Data

C Ke, D Bandyopadhyay, M Acunzo, R Winn - Onco, 2022 - mdpi.com
Background: Advances in sequencing technologies have allowed collection of massive
genome-wide information that substantially advances lung cancer diagnosis and prognosis …