Ivermectin for preventing and treating COVID‐19

M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …

Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 (COVID-19) infections

MJ Kratochvil, G Kaber, S Demirdjian, PC Cai… - medRxiv, 2022 - pmc.ncbi.nlm.nih.gov
Thick, viscous respiratory secretions are a major pathogenic feature of COVID-19 disease,
but the composition and physical properties of these secretions are poorly understood. We …

The prognostic capacity of the radiographic assessment for lung edema score in patients with COVID-19 acute respiratory distress syndrome—an international …

CMA Valk, C Zimatore, G Mazzinari, C Pierrakos… - Frontiers in …, 2022 - frontiersin.org
Background: The radiographic assessment for lung edema (RALE) score has an association
with mortality in patients with acute respiratory distress syndrome (ARDS). It is uncertain …

Same but different? Comparing the epidemiology, treatments and outcomes of COVID-19 and non-COVID-19 ARDS cases in Germany using a sample of claims data …

E Bernauer, F Alebrand, M Heurich - Viruses, 2023 - mdpi.com
Background: Acute respiratory distress syndrome (ARDS) is a severe lung condition that can
be caused by a variety of underlying illnesses. Due to SARS-CoV-2, the number of cases …

Host and viral proteins involved in SARS‐CoV‐2 infection differentially bind heme

MT Hopp, DC Rathod, D Imhof - Protein Science, 2022 - Wiley Online Library
In most severe cases, SARS‐CoV‐2‐induced autoimmune reactions have been associated
with hemolytic complications. Hemolysis‐derived heme from ruptured red blood cells has …

[HTML][HTML] The RALE score versus the ct severity score in invasively ventilated COVID-19 patients—a retrospective study comparing their prognostic capacities

CM Valk, C Zimatore, G Mazzinari, C Pierrakos… - Diagnostics, 2022 - mdpi.com
Background: Quantitative radiological scores for the extent and severity of pulmonary
infiltrates based on chest radiography (CXR) and computed tomography (CT) scan are …

Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with …

N Al-Yousif, S Komanduri, H Qurashi, A Korzhuk… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To reliably quantify the radiographic severity of COVID-19 pneumonia with the
Radiographic Assessment of Lung Edema (RALE) score on clinical chest X-rays among …

Extracorporeal membrane oxygenation aggravates platelet glycoprotein V shedding and δ-granule deficiency in COVID-19–associated acute respiratory distress …

J Herrmann, LJ Weiss, B Just, K Mott, M Drayss… - Journal of Thrombosis …, 2024 - Elsevier
Background Extracorporeal membrane oxygenation (ECMO) is a lifesaving therapy in
patients with acute respiratory distress syndrome (ARDS). Hemostatic complications are …

ARDS Mortality Prediction Model Using Evolving Clinical Data and Chest Radiograph Analysis

A Cysneiros, T Galvão, N Domingues, P Jorge, L Bento… - Biomedicines, 2024 - mdpi.com
Introduction: Within primary ARDS, SARS-CoV-2-associated ARDS (C-ARDS) emerged in
late 2019, reaching its peak during the subsequent two years. Recent efforts in ARDS …

Hyaluronan is abundant in COVID-19 respiratory secretions

G Kaber, MJ Kratochvil, EB Burgener, EL Peltan… - medRxiv, 2020 - medrxiv.org
COVID-19 respiratory infections are associated with copious, adherent respiratory
secretions that prolong chronic ventilation and contribute to the morbidity and mortality …