▪ Abstract The events leading to transcription of eukaryotic protein-coding genes culminate
in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which …

The archaeal basal transcription machinery resembles the core components of the eucaryal
RNA polymerase II apparatus. Thus, studies of the archaeal basal machinery over the last …

Pheromones are cell type-specific signals used for communication between individuals of
the same species. When faced with overcrowding or starvation, Caenorhabditis elegans …

We present homologies between archaeal and eucaryal DNA-dependent RNA polymerase
(RNAP) subunits and transcription factors. The sequences of the Sulfolobus acidocaldarius …

Abstract Analysis of the genome sequence of the small hyperthermophilic archaeal parasite
Nanoarchaeum equitans, has not revealed genes encoding the glutamate, histidine …

Mercury resistance mediated by mercuric reductase (MerA) is widespread among bacteria
and operates under the control of MerR. MerR represents a unique class of transcription …

Glutamine synthetase (GS), an essential enzyme in ammonia assimilation and glutamine
biosynthesis, has three distinctive types: GSI, GSII and GSIII. Genes for GSI have been found …

The gene encoding the hyperthermophilic extracellular alpha-amylase from Pyrococcus
furiosus was cloned by activity screening in Escherichia coli. The gene encoded a single …

Previous studies have shown that the hyperthermophilic archaeon Pyrococcus furiosus
contains four distinct cytoplasmic 2-ketoacid oxidoreductases (ORs) which differ in their …

Archaea possess a basal transcriptional apparatus that resembles that of eukaryotes. Here
we report the 2.1-Å crystal structure of the archaeal transcription factor complex formed by …