Pathophysiology of spinal cord injury
LD Hachem, MG Fehlings - Neurosurgery Clinics, 2021 - neurosurgery.theclinics.com
Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …
In vivo functions of p75NTR: Challenges and opportunities for an emerging therapeutic target
SC Malik, EG Sozmen, B Baeza-Raja… - Trends in …, 2021 - cell.com
The p75 neurotrophin receptor (p75 NTR) functions at the molecular nexus of cell death,
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …
Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury
N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …
Nerve growth factor pathobiology during the progression of Alzheimer's disease
The current review summarizes the pathobiology of nerve growth factor (NGF) and its
cognate receptors during the progression of Alzheimer's disease (AD). Both transcript and …
cognate receptors during the progression of Alzheimer's disease (AD). Both transcript and …
[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives
N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …
Progression of mesenchymal stem cell regulation on imbalanced microenvironment after spinal cord injury
Y Liu, C Zhao, R Zhang, Y Pang, L Li… - Stem Cell Research & …, 2024 - Springer
Spinal cord injury (SCI) results in significant neural damage and inhibition of axonal
regeneration due to an imbalanced microenvironment. Extensive evidence supports the …
regeneration due to an imbalanced microenvironment. Extensive evidence supports the …
Axonal growth inhibitors and their receptors in spinal cord injury: from biology to clinical translation
SS Chambel, CD Cruz - Neural Regeneration Research, 2023 - journals.lww.com
Axonal growth inhibitors are released during traumatic injuries to the adult mammalian
central nervous system, including after spinal cord injury. These molecules accumulate at …
central nervous system, including after spinal cord injury. These molecules accumulate at …
P75 neurotrophin receptor as a therapeutic target for drug development to treat neurological diseases
The interaction of neurotrophins with their receptors is involved in the pathogenesis and
progression of various neurological diseases, including Alzheimer's disease, Parkinson's …
progression of various neurological diseases, including Alzheimer's disease, Parkinson's …
The effect of iPS-derived neural progenitors seeded on laminin-coated pHEMA-MOETACl hydrogel with dual porosity in a rat model of chronic spinal cord injury
J Ruzicka, N Romanyuk, K Jirakova… - Cell …, 2019 - journals.sagepub.com
Spinal cord injury (SCI), is a devastating condition leading to the loss of locomotor and
sensory function below the injured segment. Despite some progress in acute SCI treatment …
sensory function below the injured segment. Despite some progress in acute SCI treatment …
[HTML][HTML] Acetyl-11-keto-beta-boswellic acid promotes sciatic nerve repair after injury: Molecular mechanism
Y Wang, ZL **ong, XL Ma, C Zhou… - Neural Regeneration …, 2022 - journals.lww.com
Previous studies showed that acetyl-11-keto-beta-boswellic acid (AKBA), the active
ingredient in the natural Chinese medicine Boswellia, can stimulate sciatic nerve injury …
ingredient in the natural Chinese medicine Boswellia, can stimulate sciatic nerve injury …