The mathematics of cancer: integrating quantitative models
Mathematical modelling approaches have become increasingly abundant in cancer
research. The complexity of cancer is well suited to quantitative approaches as it provides …
research. The complexity of cancer is well suited to quantitative approaches as it provides …
[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …
generated from the same patients to better understand the molecular and clinical features of …
Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data
W Yang, NM Warrington, SJ Taylor… - Science translational …, 2019 - science.org
Sex differences in the incidence and outcome of human disease are broadly recognized but,
in most cases, not sufficiently understood to enable sex-specific approaches to treatment …
in most cases, not sufficiently understood to enable sex-specific approaches to treatment …
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
Most cancers in humans are large, measuring centimetres in diameter, and composed of
many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as …
many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as …
The 2019 mathematical oncology roadmap
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
The biology and mathematical modelling of glioma invasion: a review
JCL Alfonso, K Talkenberger… - Journal of the …, 2017 - royalsocietypublishing.org
Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …
limited life expectancy. The most important hallmark of this type of tumour is its invasive …
Advances in glioblastoma multiforme treatment: new models for nanoparticle therapy
The most lethal form of brain cancer, glioblastoma multiforme, is characterized by rapid
growth and invasion facilitated by cell migration and degradation of the extracellular matrix …
growth and invasion facilitated by cell migration and degradation of the extracellular matrix …
Improving cancer treatments via dynamical biophysical models
Despite significant advances in oncological research, cancer nowadays remains one of the
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …
Patient-specific, mechanistic models of tumor growth incorporating artificial intelligence and big data
Despite the remarkable advances in cancer diagnosis, treatment, and management over the
past decade, malignant tumors remain a major public health problem. Further progress in …
past decade, malignant tumors remain a major public health problem. Further progress in …
Mathematical models of tumor cell proliferation: A review of the literature
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …
the generative properties of cancer cells span all biological scales: from genetic deviations …