Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques

LA Clifton, RA Campbell, F Sebastiani… - Advances in Colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …

[HTML][HTML] Neutron reflectometry as a powerful tool to elucidate membrane interactions of drug delivery systems

L Caselli, T Nylander, M Malmsten - Advances in Colloid and Interface …, 2024 - Elsevier
The last couple of decades have seen an explosion of novel colloidal drug delivery systems,
which have been demonstrated to increase drug efficacy, reduce side-effects, and provide …

Supported lipid bilayer formation: beyond vesicle fusion

JA Jackman, NJ Cho - Langmuir, 2020 - ACS Publications
Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed
on solid surfaces and integrated with a wide range of surface-sensitive measurement …

Exploring the Membrane-Active Interactions of Antimicrobial Long-Chain Fatty Acids Using a Supported Lipid Bilayer Model for Gram-Positive Bacterial Membranes

S Shin, J Yu, H Tae, Y Zhao, D Jiang… - … Applied Materials & …, 2024 - ACS Publications
The dynamic nature of bacterial lipid membranes significantly impacts the efficacy of
antimicrobial therapies. However, traditional assay methods often fall short in replicating the …

[HTML][HTML] Atomic force microscopy to elucidate how peptides disrupt membranes

K Hammond, MG Ryadnov… - Biochimica et Biophysica …, 2021 - Elsevier
Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …

The persistence-inducing toxin HokB forms dynamic pores that cause ATP leakage

D Wilmaerts, M Bayoumi, L Dewachter, W Knapen… - MBio, 2018 - journals.asm.org
Bacterial populations harbor a small fraction of cells that display transient multidrug
tolerance. These so-called persister cells are extremely difficult to eradicate and contribute …

Recent applications of synchrotron radiation and neutrons in the study of soft matter

T Narayanan, H Wacklin, O Konovalov… - Crystallography …, 2017 - Taylor & Francis
The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …

[HTML][HTML] Understanding the formation of supported lipid bilayers via vesicle fusion—A case that exemplifies the need for the complementary method approach

TK Lind, M Cárdenas - Biointerphases, 2016 - pubs.aip.org
In this review, the authors discuss the challenges of studying supported lipid bilayers (SLBs)
deposited by vesicle fusion in terms of (1) evaluating SLB formation and quality using quartz …

Simultaneous Multipass Resistive-Pulse Sensing and Fluorescence Imaging of Liposomes

AJ Schmeltzer, EM Peterson, JM Harris, DK Lathrop… - ACS …, 2024 - ACS Publications
Simultaneous multipass resistive-pulse sensing and fluorescence imaging have been used
to correlate the size and fluorescence intensity of individual E. coli lipid liposomes …

Facile generation of biomimetic-supported lipid bilayers on conducting polymer surfaces for membrane biosensing

H Su, HY Liu, AM Pappa, TC Hidalgo… - … Applied Materials & …, 2019 - ACS Publications
Membrane biosensors that can rapidly sense pathogen interaction and disrupting agents
are needed to identify and screen new drugs to combat antibiotic resistance. Bioelectronic …