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Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …
membranes or biomembranes are used as platforms to understand fundamental properties …
[HTML][HTML] Neutron reflectometry as a powerful tool to elucidate membrane interactions of drug delivery systems
The last couple of decades have seen an explosion of novel colloidal drug delivery systems,
which have been demonstrated to increase drug efficacy, reduce side-effects, and provide …
which have been demonstrated to increase drug efficacy, reduce side-effects, and provide …
Supported lipid bilayer formation: beyond vesicle fusion
JA Jackman, NJ Cho - Langmuir, 2020 - ACS Publications
Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed
on solid surfaces and integrated with a wide range of surface-sensitive measurement …
on solid surfaces and integrated with a wide range of surface-sensitive measurement …
Exploring the Membrane-Active Interactions of Antimicrobial Long-Chain Fatty Acids Using a Supported Lipid Bilayer Model for Gram-Positive Bacterial Membranes
The dynamic nature of bacterial lipid membranes significantly impacts the efficacy of
antimicrobial therapies. However, traditional assay methods often fall short in replicating the …
antimicrobial therapies. However, traditional assay methods often fall short in replicating the …
[HTML][HTML] Atomic force microscopy to elucidate how peptides disrupt membranes
K Hammond, MG Ryadnov… - Biochimica et Biophysica …, 2021 - Elsevier
Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …
The persistence-inducing toxin HokB forms dynamic pores that cause ATP leakage
Bacterial populations harbor a small fraction of cells that display transient multidrug
tolerance. These so-called persister cells are extremely difficult to eradicate and contribute …
tolerance. These so-called persister cells are extremely difficult to eradicate and contribute …
Recent applications of synchrotron radiation and neutrons in the study of soft matter
T Narayanan, H Wacklin, O Konovalov… - Crystallography …, 2017 - Taylor & Francis
The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …
[HTML][HTML] Understanding the formation of supported lipid bilayers via vesicle fusion—A case that exemplifies the need for the complementary method approach
In this review, the authors discuss the challenges of studying supported lipid bilayers (SLBs)
deposited by vesicle fusion in terms of (1) evaluating SLB formation and quality using quartz …
deposited by vesicle fusion in terms of (1) evaluating SLB formation and quality using quartz …
Simultaneous Multipass Resistive-Pulse Sensing and Fluorescence Imaging of Liposomes
Simultaneous multipass resistive-pulse sensing and fluorescence imaging have been used
to correlate the size and fluorescence intensity of individual E. coli lipid liposomes …
to correlate the size and fluorescence intensity of individual E. coli lipid liposomes …
Facile generation of biomimetic-supported lipid bilayers on conducting polymer surfaces for membrane biosensing
Membrane biosensors that can rapidly sense pathogen interaction and disrupting agents
are needed to identify and screen new drugs to combat antibiotic resistance. Bioelectronic …
are needed to identify and screen new drugs to combat antibiotic resistance. Bioelectronic …