Decompensated liver disease is complicated by multi‐organ failure and poor prognosis. The
prognosis of patients with liver failure often dictates clinical management. Current prognostic …

Background. Cirrhosis is associated with abnormal autonomic function and regulation of
cardiac rhythm. Measurement of heart rate variability (HRV) provides an accurate and non …

Pulse oximetry is routinely used for monitoring patients' oxygen saturation levels with little
regard to the variability of this physiological variable. There are few published studies on …

The Poincaré plot is a geometrical technique used to visualize and quantify the correlation
between two consecutive data points in a time-series. Since the dynamics of fluctuations in …

Normal human breathing exhibits complex variability in both respiratory rhythm and volume.
Analyzing such nonlinear fluctuations may provide clinically relevant information in patients …

Recent studies have found that oxygen saturation (SpO2) variability analysis has potential
for noninvasive assessment of the functional connectivity of cardiorespiratory control …

New Findings What is the central question of this study? What is the physiological
interpretation of fluctuations observed during normobaric hypoxia in healthy individuals …

Assessing illness severity in the intensive care unit (ICU) is crucial for early prediction of
deterioration and prognosis. Traditional prognostic scores often treat organ systems …

Background: The study is the first to evaluate the effects of graded normobaric hypoxia on
SpO2 variability in healthy individuals. Materials and Methods: Twelve healthy males (mean …

Background: Liver cirrhosis is a complex disorder, involving several different organ systems
and physiological network disruption. Various physiological markers have been developed …