Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial imaging of glycoRNAs in single cells
Glycosylated RNAs (glycoRNAs) have recently emerged as a new class of molecules of
substantial interest owing to their potential roles in cellular processes and diseases …
substantial interest owing to their potential roles in cellular processes and diseases …
Sugar Highs: Recent Notable Breakthroughs in Glycobiology
J Hu, DT Huynh, M Boyce - Biochemistry, 2024 - ACS Publications
Glycosylation is biochemically complex and functionally critical to a wide range of processes
and disease states, making it a vibrant area of contemporary research. Here, we highlight a …
and disease states, making it a vibrant area of contemporary research. Here, we highlight a …
N-glycosylated molecules act as a co-precipitant in RNA purification
A recent ground-breaking study suggested that small RNA from mammalian cells can
undergo N-glycan modifications (termed glycoRNA). The discovery relied upon a metabolic …
undergo N-glycan modifications (termed glycoRNA). The discovery relied upon a metabolic …
Cell-Surface RNA Associates with Heparan Sulfate and RNA-Binding Proteins to Modulate Receptor-Ligand Interactions
Recent discoveries have shown the presence of RNA molecules on the cell surface, defying
the traditional view that RNA only functions intracellularly. However, it is not well understood …
the traditional view that RNA only functions intracellularly. However, it is not well understood …
Cell surface RNA expression modulates alveolar epithelial function
Glycosylated RNA (glycoRNA) has recently emerged as a novel constituent of the glycocalyx
on cell surfaces, yet its biological functions remain largely unexplored. In this report, we …
on cell surfaces, yet its biological functions remain largely unexplored. In this report, we …
A draft of human N-glycans of glycoRNA
M Bi, Z Zhang, T Wang, H Liang, Z Tian - bioRxiv, 2023 - biorxiv.org
In addition to the backbone molecules of proteins and lipids, RNAs have recently been
found to be N-glycosylated as well in cell models. Some overlap of N-glycans between RNA …
found to be N-glycosylated as well in cell models. Some overlap of N-glycans between RNA …