Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

Blood is a tissue with high cellular turnover, and its production is a tightly orchestrated
process that requires constant replenishment. All mature blood cells are generated from …

Once thought to be rare disorders, the myelodysplastic syndromes (MDS) are now
recognized as among the most common hematological neoplasms, probably affecting> 30 …

In β-thalassemia, unequal production of α-and β-globin chains in erythroid precursors
causes apoptosis and inhibition of late-stage erythroid differentiation, leading to anemia …

The transforming growth factor (TGF)-β superfamily comprises more than 30 soluble growth
factors that play a central role in erythropoiesis and are part of a tightly regulated …

The present study aims to investigate the relation between exposure to low-dose benzene
and the occurrence of oxidative DNA damage in gasoline station workers, as well as the …

Mesenchymal stromal cells are involved in the pathogenesis of myelodysplastic syndromes
and acute myeloid leukemia, but the underlying mechanisms are incompletely understood …

Myelosysplastic syndromes (MDS) include a heterogeneous group of clonal myeloid
neoplasms characterized by ineffective hematopoiesis leading to blood cytopenias and a …

Aims Benzene metabolism seems to modulate NF-κB, p38-MAPK (mitogen-activated protein
kinase) and signal transducer and activator of transcription 3 (STAT3) signalling pathways …

Autoimmune and inflammatory conditions (AICs) are encountered in up to 25% of patients
with myelodysplastic syndromes (MDS). A wide range of AICs have been reported in …