The journey of islet cell transplantation and future development

A Gamble, AR Pepper, A Bruni, AMJ Shapiro - Islets, 2018 - Taylor & Francis
Intraportal islet transplantation has proven to be efficacious in preventing severe
hypoglycemia and restoring insulin independence in selected patients with type 1 diabetes …

Post-liver transplantation diabetes mellitus: a review of relevance and approach to treatment

MJ Peláez-Jaramillo, AA Cárdenas-Mojica, PV Gaete… - Diabetes Therapy, 2018 - Springer
Post-liver transplantation diabetes mellitus (PLTDM) develops in up to 30% of liver
transplant recipients and is associated with increased risk of mortality and multiple morbid …

Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro

E Matsa, PW Burridge, KH Yu, JH Ahrens… - Cell stem cell, 2016 - cell.com
Understanding individual susceptibility to drug-induced cardiotoxicity is key to improving
patient safety and preventing drug attrition. Human induced pluripotent stem cells (hiPSCs) …

The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

GA Salg, NA Giese, M Schenk… - Journal of tissue …, 2019 - journals.sagepub.com
A bioartificial endocrine pancreas is proposed as a future alternative to current treatment
options. Patients with insulin-secretion deficiency might benefit. This is the first systematic …

Metabolic complications in liver transplant recipients

M Jiménez-Pérez, R González-Grande… - World journal of …, 2016 - pmc.ncbi.nlm.nih.gov
The metabolic syndrome (MS), which includes obesity, dyslipidaemia, hypertension and
hyperglycaemia according to the most widely accepted definitions now used, is one of the …

Metabolic consequences of modern immunosuppressive agents in solid organ transplantation

O Bamgbola - Therapeutic advances in endocrinology and …, 2016 - journals.sagepub.com
Among other factors, sophistication of immunosuppressive (IS) regimen accounts for the
remarkable success attained in the short-and medium-term solid organ transplant (SOT) …

Genetics of new-onset diabetes after transplantation

JA McCaughan, AJ McKnight… - Journal of the American …, 2014 - journals.lww.com
New-onset diabetes after transplantation is a common complication that reduces recipient
survival. Research in renal transplant recipients has suggested that pancreatic β-cell …

Approach to the patient with new-onset diabetes after transplant (NODAT)

JT Lane, S Dagogo-Jack - The Journal of Clinical Endocrinology …, 2011 - academic.oup.com
New-onset diabetes after transplantation (NODAT) refers to the occurrence of diabetes in
previously nondiabetic persons after organ transplantation. The incidence rates of NODAT …

Diabetes care after transplant: definitions, risk factors, and clinical management

A Wallia, V Illuri, ME Molitch - Medical Clinics, 2016 - medical.theclinics.com
Patients who undergo solid organ transplantation may have preexisting diabetes mellitus
(DM), which puts them at increased risk from any surgery. 1 It is important to evaluate the …

Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity

P Li, R Zhang, J Zhou, P Guo, Y Liu, S Shi - Gut Microbes, 2024 - Taylor & Francis
Up to 40% of transplant recipients treated long-term with tacrolimus (TAC) develop post-
transplant diabetes mellitus (PTDM). TAC is an important risk factor for PTDM, but is also …