The lung microenvironment: an important regulator of tumour growth and metastasis

NK Altorki, GJ Markowitz, D Gao, JL Port… - Nature Reviews …, 2019 - nature.com
Lung cancer is a major global health problem, as it is the leading cause of cancer-related
deaths worldwide. Major advances in the identification of key mutational alterations have led …

Overcoming resistance to tumor-targeted and immune-targeted therapies

M Aldea, F Andre, A Marabelle, S Dogan… - Cancer …, 2021 - aacrjournals.org
Resistance to anticancer therapies includes primary resistance, usually related to lack of
target dependency or presence of additional targets, and secondary resistance, mostly …

[HTML][HTML] Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases

A Fallah, A Sadeghinia, H Kahroba, A Samadi… - Biomedicine & …, 2019 - Elsevier
Angiogenesis is a critical step in the progression of almost all human malignancies and
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …

Monotherapy and combination therapy using anti‐angiogenic nanoagents to fight cancer

P Liang, B Ballou, X Lv, W Si, MP Bruchez… - Advanced …, 2021 - Wiley Online Library
Anti‐angiogenic therapy, targeting vascular endothelial cells (ECs) to prevent tumor growth,
has been attracting increasing attention in recent years, beginning with bevacizumab …

Vasculogenic mimicry formation in EBV-associated epithelial malignancies

T **ang, YX Lin, W Ma, HJ Zhang, KM Chen… - Nature …, 2018 - nature.com
Abstract Epstein-Barr virus (EBV)-associated epithelial cancers, including nasopharyngeal
carcinoma (NPC) and approximately 10% of gastric cancers, termed EBVaGC, represent …

Therapeutic application of anti-angiogenic nanomaterials in cancers

S Mukherjee, CR Patra - Nanoscale, 2016 - pubs.rsc.org
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, plays a vital
role in physiological and pathological processes (embryonic development, wound healing …

Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression

L Yang, PC Lin - Seminars in cancer biology, 2017 - Elsevier
Abstract Treatment of cancer metastasis has been largely ineffective. It is paramount to
understand the mechanisms underlying the metastatic process, of which the tumor …

Nanocarrier design–function relationship: the prodigious role of properties in regulating biocompatibility for drug delivery applications

AO Oladipo, SL Lebelo, TAM Msagati - Chemico-Biological Interactions, 2023 - Elsevier
The concept of drug delivery systems as a magic bullet for the delivery of bioactive
compounds has emerged as a promising approach in the treatment of different diseases …

Cancer-associated angiogenesis: the endothelial cell as a checkpoint for immunological patrolling

AG Solimando, SD Summa, A Vacca, D Ribatti - Cancers, 2020 - mdpi.com
Simple Summary A clinical decision and study design investigating the level and extent of
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic …

Pivotal role for decorin in angiogenesis

H Järveläinen, A Sainio, TN Wight - Matrix Biology, 2015 - Elsevier
Angiogenesis, the formation of new blood vessels from preexisting vessels, is a highly
complex process. It is regulated in a finely-tuned manner by numerous molecules including …