Integrated modelling of biological systems is becoming a necessity for constructing models
containing the major biochemical processes of such systems in order to obtain a holistic …

Owing to the availability of data of one biological phenomenon at different levels/scales,
modelling of biological systems is moving from single level/scale to multiple levels/scales …

Computational biological models have proven to be an invaluable tool for understanding
and predicting the behaviour of many biological systems. While it may not be too …

Studying and analysing the various phases and key proteins of cell cycles is essential for the
understanding of cell development and differentiation. To this end, mechanistic models play …

With the steady advance of in-silico biological experimentation, model construction and
simulation becomes a ubiquitous tool to understand and predict the behaviour of many …

We consider coloured Petri nets, qualitative and quantitative ones alike, as supported by our
PetriNuts tool family, comprising, among others, Snoopy, Marcie and Spike. Currently, most …

The bio-cell cycle is controlled by a complex biochemical network of signaling pathways.
Modeling such challenging networks accurately is imperative for the understanding of their …

Abstract Multi-Drug Resistant (MDR) and Extensively Drug-Resistant (XDR) in Tuberculosis
(TB) is still a big threat worldwide, as it remains one of the leading causes of death. The …

Whole-cell modeling aims to incorporate all main genes and processes, and their
interactions of a cell in one model. Whole-cell modeling has been regarded as the central …

Some infectious diseases such as COVID-19 have the characteristics of long incubation
period, high infectivity during the incubation period, and carriers with mild or no symptoms …