The acute stress response in the multiomic era

A Floriou-Servou, L von Ziegler, R Waag, C Schläppi… - Biological …, 2021 - Elsevier
Studying the stress response is a major pillar of neuroscience research not only because
stress is a daily reality but also because the exquisitely fine-tuned bodily changes triggered …

Brain glycogen metabolism: A possible link between sleep disturbances, headache and depression

JM Petit, E Eren-Koçak, H Karatas, P Magistretti… - Sleep Medicine …, 2021 - Elsevier
The functions of sleep and its links with neuropsychiatric diseases have long been
questioned. Among the numerous hypotheses on sleep function, early studies proposed that …

Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress

M Weger, D Alpern, A Cherix, S Ghosal, J Grosse… - Scientific reports, 2020 - nature.com
Mitochondrial dysfunction was highlighted as a crucial vulnerability factor for the
development of depression. However, systemic studies assessing stress-induced changes …

Acute ketamine facilitates fear memory extinction in a rat model of PTSD along with restoring glutamatergic alterations and dendritic atrophy in the prefrontal cortex

N Sala, C Paoli, T Bonifacino, J Mingardi… - Frontiers in …, 2022 - frontiersin.org
Stress represents a major risk factor for psychiatric disorders, including post-traumatic stress
disorder (PTSD). Recently, we dissected the destabilizing effects of acute stress on the …

[HTML][HTML] Effects of chronic stress on cognitive function–from neurobiology to intervention

M Girotti, SE Bulin, FR Carreno - Neurobiology of Stress, 2024 - Elsevier
Exposure to chronic stress contributes considerably to the development of cognitive
impairments in psychiatric disorders such as depression, generalized anxiety disorder …

Molecular signatures of astrocytes and microglia maladaptive responses to acute stress are rescued by a single administration of ketamine in a rodent model of PTSD

M Valenza, R Facchinetti, C Torazza, C Ciarla… - Translational …, 2024 - nature.com
Stress affects the brain and alters its neuroarchitecture and function; these changes can be
severe and lead to psychiatric disorders. Recent evidence suggests that astrocytes and …

Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress

T Bonifacino, J Mingardi, R Facchinetti, N Sala… - Translational …, 2023 - nature.com
Stress represents a main risk factor for psychiatric disorders. Whereas it is known that even a
single trauma may induce psychiatric disorders in humans, the mechanisms of vulnerability …

Brainstem transcriptomic changes in male Wistar rats after acute stress, comparing the use of duplex specific nuclease (DSN)

DA Lanshakov, EV Sukhareva, VV Bulygina… - Scientific Reports, 2024 - nature.com
In this work, we have analyzed the transcriptomic changes in the brainstem of male Wistar
rats 2 h after an acute stress exposure. We performed duplex-specific nuclease …

Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease

M Xue, Y Zeng, R Lin, HQ Qu, T Zhang… - Experimental …, 2021 - journals.sagepub.com
While there is no cure for chronic obstructive pulmonary disease (COPD), its progressive
nature and the formidable challenge to manage its symptoms warrant a more extensive …

High fructose diet induces sex-specific modifications in synaptic respiration and affective-like behaviors in rats

A Kloster, MM Hyer, S Dyer, C Salome-Sanchez… - Neuroscience, 2021 - Elsevier
The consequences of excessive fructose intake extend beyond those of metabolic disorder
to changes in emotional regulation and cognitive function. Long-term consumption of …