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The acute stress response in the multiomic era
Studying the stress response is a major pillar of neuroscience research not only because
stress is a daily reality but also because the exquisitely fine-tuned bodily changes triggered …
stress is a daily reality but also because the exquisitely fine-tuned bodily changes triggered …
Brain glycogen metabolism: A possible link between sleep disturbances, headache and depression
The functions of sleep and its links with neuropsychiatric diseases have long been
questioned. Among the numerous hypotheses on sleep function, early studies proposed that …
questioned. Among the numerous hypotheses on sleep function, early studies proposed that …
Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress
Mitochondrial dysfunction was highlighted as a crucial vulnerability factor for the
development of depression. However, systemic studies assessing stress-induced changes …
development of depression. However, systemic studies assessing stress-induced changes …
Acute ketamine facilitates fear memory extinction in a rat model of PTSD along with restoring glutamatergic alterations and dendritic atrophy in the prefrontal cortex
N Sala, C Paoli, T Bonifacino, J Mingardi… - Frontiers in …, 2022 - frontiersin.org
Stress represents a major risk factor for psychiatric disorders, including post-traumatic stress
disorder (PTSD). Recently, we dissected the destabilizing effects of acute stress on the …
disorder (PTSD). Recently, we dissected the destabilizing effects of acute stress on the …
[HTML][HTML] Effects of chronic stress on cognitive function–from neurobiology to intervention
M Girotti, SE Bulin, FR Carreno - Neurobiology of Stress, 2024 - Elsevier
Exposure to chronic stress contributes considerably to the development of cognitive
impairments in psychiatric disorders such as depression, generalized anxiety disorder …
impairments in psychiatric disorders such as depression, generalized anxiety disorder …
Molecular signatures of astrocytes and microglia maladaptive responses to acute stress are rescued by a single administration of ketamine in a rodent model of PTSD
M Valenza, R Facchinetti, C Torazza, C Ciarla… - Translational …, 2024 - nature.com
Stress affects the brain and alters its neuroarchitecture and function; these changes can be
severe and lead to psychiatric disorders. Recent evidence suggests that astrocytes and …
severe and lead to psychiatric disorders. Recent evidence suggests that astrocytes and …
Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress
T Bonifacino, J Mingardi, R Facchinetti, N Sala… - Translational …, 2023 - nature.com
Stress represents a main risk factor for psychiatric disorders. Whereas it is known that even a
single trauma may induce psychiatric disorders in humans, the mechanisms of vulnerability …
single trauma may induce psychiatric disorders in humans, the mechanisms of vulnerability …
Brainstem transcriptomic changes in male Wistar rats after acute stress, comparing the use of duplex specific nuclease (DSN)
DA Lanshakov, EV Sukhareva, VV Bulygina… - Scientific Reports, 2024 - nature.com
In this work, we have analyzed the transcriptomic changes in the brainstem of male Wistar
rats 2 h after an acute stress exposure. We performed duplex-specific nuclease …
rats 2 h after an acute stress exposure. We performed duplex-specific nuclease …
Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease
M Xue, Y Zeng, R Lin, HQ Qu, T Zhang… - Experimental …, 2021 - journals.sagepub.com
While there is no cure for chronic obstructive pulmonary disease (COPD), its progressive
nature and the formidable challenge to manage its symptoms warrant a more extensive …
nature and the formidable challenge to manage its symptoms warrant a more extensive …
High fructose diet induces sex-specific modifications in synaptic respiration and affective-like behaviors in rats
A Kloster, MM Hyer, S Dyer, C Salome-Sanchez… - Neuroscience, 2021 - Elsevier
The consequences of excessive fructose intake extend beyond those of metabolic disorder
to changes in emotional regulation and cognitive function. Long-term consumption of …
to changes in emotional regulation and cognitive function. Long-term consumption of …