The direct activation of inert saturated C–H bonds for selective functionalization has long
been a significant challenge in organic synthesis. The past few decades have witnessed the …

Sulfonamides, with the general formula R-SO2NR1R2, have attracted great attention since
the early discovery of sulfonamide-containing antibacterial drugs. The combinations of …

Herein, we report the synthesis of a series of new quinazoline sulfonamide conjugates 2–16
and their evaluation as potential anticancer agents via dual targeting of EGFR T790M and …

Citrus canker is a disease of economic importance and there are limited biocontrol agents
available to mitigate it in an integrated manner. This study was conducted to combat citrus …

In this study, eleven novel chromene sulfonamide hybrids were synthesized by a convenient
method in accordance with green chemistry. At first, chromene derivatives (1–9a) were …

A library of 2-oxopyridine carbonitriles 1–34 was synthesized by regioselective nucleophilic
substitution reactions. In the first step, a one-pot multicomponent reaction yield pyridone …

Herein, we report the synthesis of a series of new fourteen iodoquinazoline derivatives 7a-c
to 13a-e and their evaluation as potential anticancer agents via dual targeting of EGFR …

In the dynamic area of drug development, researchers have been urged to uncover and test
novel compounds with better effectiveness and fewer side effects in order to find more …

Our knowledge of fluorine's unique and complex properties has significantly increased over
the past 20 years. Consequently, more sophisticated and innovative techniques have …

A series comprising 30 novel benzenesulfonamide bearing 1, 2, 4-triazoles 1a–1h, 2a–2h,
3a–3h, 4b–4f and 4h has been synthesized and investigated as anti-microbial and anti …