This Review summarizes the advances in the construction of all-carbon quaternary
stereocenters via catalytic enantioselective desymmetrization of prochiral and meso …

London dispersion (LD) interactions are the main contribution of the attractive part of the van
der Waals potential. Even though LD effects are the driving force for molecular aggregation …

Site-and stereoselective C–H functionalization is highly challenging in the synthetic
chemistry community. Although the chemistry of vinyl cations has been vigorously studied in …

Chemoenzymatic dynamic kinetic resolution (DKR) constitutes a convenient and efficient
method to access enantiomerically pure alcohol and amine derivatives. This Perspective …

Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Over the last ten years there has been a huge increase in development and applications of
organocatalysis in which the catalyst acts as a nucleophile. Amidines and guanidines are …

Organocatalytic enantioselective desymmetrisation of achiral or meso compounds is a
powerful strategy for the construction of enantiomerically enriched complex molecules, often …

This review covers the recent developments (since 2015) of enantioselective
desymmetrization reactions using metal-catalyzed, organocatalyzed and enzymatic …

Chiral tertiary alcohols are an important class of organic compounds which have found wide
applications in both academia and industry. Therefore, various synthetic strategies towards …

The first N-heterocyclic carbene (NHC)-catalyzed [3+ 4] cycloaddition of azomethine imines
and enals is disclosed. Oxidative catalytic remote activation of enals affords 1, 4 …