Advances in the pathogenesis of psoriasis: from keratinocyte perspective
X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …
Metabolism of immune cells in cancer
RD Leone, JD Powell - Nature reviews cancer, 2020 - nature.com
Through the successes of checkpoint blockade and adoptive cellular therapy,
immunotherapy has become an established treatment modality for cancer. Cellular …
immunotherapy has become an established treatment modality for cancer. Cellular …
Lactate modulation of immune responses in inflammatory versus tumour microenvironments
The microenvironment in cancerous tissues is immunosuppressive and pro-tumorigenic,
whereas the microenvironment of tissues affected by chronic inflammatory disease is pro …
whereas the microenvironment of tissues affected by chronic inflammatory disease is pro …
Targeting immunometabolism as an anti-inflammatory strategy
The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system
T Wang, Z Jian, A Baskys, J Yang, J Li, H Guo, Y Hei… - Biomaterials, 2020 - Elsevier
Oxidative stress is a major cause of skin injury induced by damaging stimuli such as UV
radiation. Currently, owing to their immunomodulatory properties, mesenchymal stem cell …
radiation. Currently, owing to their immunomodulatory properties, mesenchymal stem cell …
Synthesis, bioactive properties, and biomedical applications of intrinsically therapeutic nanoparticles for disease treatment
DD Nguyen, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …
capabilities of self-triggering bioactive activities (without drug) when interacting with …
Targeting metabolism to regulate immune responses in autoimmunity and cancer
Metabolic programming is emerging as a critical mechanism to alter immune cell activation,
differentiation and function. Targeting metabolism does not completely suppress or activate …
differentiation and function. Targeting metabolism does not completely suppress or activate …
Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
Single-stranded circular RNAs (circRNAs), generated through 'backsplicing', occur more
extensively than initially anticipated. The possible functions of the vast majority of circRNAs …
extensively than initially anticipated. The possible functions of the vast majority of circRNAs …
Carboxymethyl cellulose/sericin-based hydrogels with intrinsic antibacterial, antioxidant, and anti-inflammatory properties promote re-epithelization of diabetic wounds …
Diabetic wound healing encounters significant challenges due to the extreme oxidative
stress resulting from excessive inflammation and microbial infections, disrupting the typical …
stress resulting from excessive inflammation and microbial infections, disrupting the typical …
Metabolic pathways that control skin homeostasis and inflammation
Keratinocytes and skin immune cells are actively metabolizing nutrients present in their
microenvironment. This is particularly important in common chronic inflammatory skin …
microenvironment. This is particularly important in common chronic inflammatory skin …