[HTML][HTML] Data structuring may prevent ambiguity and improve personalized medical prognosis

CR Libertin, P Kempaiah, Y Gupta, JM Fair… - Molecular Aspects of …, 2023 - Elsevier
Topics expected to influence personalized medicine (PM), where medical decisions,
practices, and treatments are tailored to the individual patient, are reviewed. Lack of …

Biologically grounded scientific methods: the challenges ahead for combating epidemics

AL Rivas, AL Hoogesteijn - Methods, 2021 - Elsevier
The protracted COVID 19 pandemic may indicate failures of scientific methodologies.
Ho** to facilitate the evaluation and/or update of methods relevant in Biomedicine, several …

Multi-cellular immunological interactions associated with COVID-19 infections

JS Verma, CR Libertin, Y Gupta, G Khanna… - Frontiers in …, 2022 - frontiersin.org
To rapidly prognosticate and generate hypotheses on pathogenesis, leukocyte multi-
cellularity was evaluated in SARS-CoV-2 infected patients treated in India or the United …

From numbers to medical knowledge: Harnessing combinatorial data patterns to predict COVID-19 resource needs and distinguish patient subsets

PH Satashia, PM Franco, AL Rivas, S Isha… - Frontiers in …, 2023 - frontiersin.org
Background The COVID-19 pandemic intensified the use of scarce resources, including
extracorporeal membrane oxygenation (ECMO) and mechanical ventilation (MV). The …

Personalized, disease-stage specific, rapid identification of immunosuppression in sepsis

T Pappa, AL Rivas, MJ Iandiorio… - Frontiers in …, 2024 - frontiersin.org
Introduction Data overlap** of different biological conditions prevents personalized
medical decision-making. For example, when the neutrophil percentages of surviving septic …

Decoding Immuno-Competence: A Novel Analysis of Complete Blood Cell Count Data in COVID-19 Outcomes

P Kempaiah, CR Libertin, RA Chitale, I Naeyma… - Biomedicines, 2024 - mdpi.com
Background: While 'immuno-competence'is a well-known term, it lacks an operational
definition. To address this omission, this study explored whether the temporal and structured …

Personalized and dynamic antibiograms-an exploration in seven infectious syndromes

MJ Iandiorio, JC Fazio, P Kempaiah, R Darvasula… - medRxiv, 2021 - medrxiv.org
To prevent antimicrobial resistance and inform better, antibiograms should distinguish
different biomedical situations. It is also desirable that new antibiograms provide in vivo …