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Synthetic genomes
W Zhang, LA Mitchell, JS Bader… - Annual review of …, 2020 - annualreviews.org
DNA synthesis technology has progressed to the point that it is now practical to synthesize
entire genomes. Quite a variety of methods have been developed, first to synthesize single …
entire genomes. Quite a variety of methods have been developed, first to synthesize single …
A review on acoustic droplet ejection technology and system
The pace of change in chemical and biological research enabled by improved detection
systems demands fundamental liquid handling and sample preparation changes. The …
systems demands fundamental liquid handling and sample preparation changes. The …
A versatile platform for locus-scale genome rewriting and verification
R Brosh, JM Laurent, R Ordoñez, E Huang… - Proceedings of the …, 2021 - pnas.org
Routine rewriting of loci associated with human traits and diseases would facilitate their
functional analysis. However, existing DNA integration approaches are limited in terms of …
functional analysis. However, existing DNA integration approaches are limited in terms of …
Synthetic genomes with altered genetic codes
N Ostrov, A Nyerges, A Chiappino-Pepe… - Current Opinion in …, 2020 - Elsevier
The genetic code is the set of rules that define how information encoded in DNA is
interpreted into amino acids to make proteins. With few naturally occurring exceptions, the …
interpreted into amino acids to make proteins. With few naturally occurring exceptions, the …
Superloser: A Plasmid Shuffling Vector for Saccharomyces cerevisiae with Exceedingly Low Background
Here we report a new plasmid shuffle vector for forcing budding yeast (Saccharomyces
cerevisiae) to incorporate a new genetic pathway in place of a native pathway–even an …
cerevisiae) to incorporate a new genetic pathway in place of a native pathway–even an …
Fast acoustic droplet ejection based on annular array transducer
Acoustic droplet ejection (ADE) has become the preferred method for liquid transfer in a
variety of applications including synthetic biology, genoty** and drug discovery …
variety of applications including synthetic biology, genoty** and drug discovery …
From kilobases to megabases: design and delivery of large DNA constructs into mammalian genomes
FG Liberante, T Ellis - Current Opinion in Systems Biology, 2021 - Elsevier
As DNA synthesis has become cheaper, it has made assembly of larger and larger genes
possible. To fully realise this opportunity for a new era of synthetic biology in mammals, a …
possible. To fully realise this opportunity for a new era of synthetic biology in mammals, a …
DNA SYNTHESIS AND SYNTHETIC GENOME
ZX **e, RY Zhu, Y Liu, YJ Yuan - Nucleic Acids in Medicinal …, 2023 - Wiley Online Library
Synthetic genomics is a nascent field with technologies rapidly developed in the past
decade. In this chapter, we review the history of synthetic genomics and a variety of …
decade. In this chapter, we review the history of synthetic genomics and a variety of …
Methods and compositions for integration of a dna construct
DM Truong - US Patent App. 18/185,601, 2023 - Google Patents
US20230295668A1 - Methods and compositions for integration of a dna construct - Google
Patents US20230295668A1 - Methods and compositions for integration of a dna construct …
Patents US20230295668A1 - Methods and compositions for integration of a dna construct …
[PDF][PDF] Big DNA as a tool to dissect an age-related macular degeneration haplotype
JM Laurent, X Fu, S German, MT Maurano, K Zhang… - bioRxiv, 2018 - biorxiv.org
Abstract Age-related Macular Degeneration (AMD) is a leading cause of blindness in the
developed world, especially in aging populations, and is therefore an important target for …
developed world, especially in aging populations, and is therefore an important target for …