Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …

Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

Mendelian randomization (MR) leverages genetic information to examine the causal
relationship between phenotypes allowing for the presence of unmeasured confounders …

While population-scale neuroimaging studies offer the promise of discovery and
characterisation of subtle risk factors, massive sample sizes increase the power for both …

Mendelian Randomisation (MR) is an increasingly popular approach that estimates the
causal effect of risk factors on complex human traits. While it has seen several extensions …

Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance
our understanding of underlying mechanisms and pathways that can be targeted. We …

Abstract Background & Aims Around 20% of patients with non-alcoholic fatty liver disease
(NAFLD) are lean. Increasing evidence suggests that lean NAFLD is a unique subtype of the …

Background With the increasing availability and size of multi‐omics datasets, investigating
the casual relationships between molecular phenotypes has become an important aspect of …

The number of studies with information at multiple biological levels of granularity, such as
genomics, proteomics, and metabolomics, is increasing each year, and a biomedical …

Orienting the causal relationship between pairs of traits is a fundamental task in scientific
research with significant implications in practice, such as in prioritizing molecular targets and …