Computational prediction of drug–target interactions using chemogenomic approaches: an empirical survey

A Ezzat, M Wu, XL Li, CK Kwoh - Briefings in bioinformatics, 2019 - academic.oup.com
Computational prediction of drug–target interactions (DTIs) has become an essential task in
the drug discovery process. It narrows down the search space for interactions by suggesting …

Data science in unveiling COVID-19 pathogenesis and diagnosis: evolutionary origin to drug repurposing

J Kumar Das, G Tradigo, P Veltri… - Briefings in …, 2021 - academic.oup.com
Motivation The outbreak of novel severe acute respiratory syndrome coronavirus (SARS-
CoV-2, also known as COVID-19) in Wuhan has attracted worldwide attention. SARS-CoV-2 …

Multi-aspect sentiment analysis for Chinese online social reviews based on topic modeling and HowNet lexicon

F **anghua, L Guo, G Yanyan, W Zhiqiang - Knowledge-Based Systems, 2013 - Elsevier
User-generated reviews on the Web reflect users' sentiment about products, services and
social events. Existing researches mostly focus on the sentiment classification of the product …

Semantic similarity analysis of protein data: assessment with biological features and issues

PH Guzzi, M Mina, C Guerra… - Briefings in …, 2012 - academic.oup.com
The integration of proteomics data with biological knowledge is a recent trend in
bioinformatics. A lot of biological information is available and is spread on different sources …

Survey of local and global biological network alignment: the need to reconcile the two sides of the same coin

PH Guzzi, T Milenković - Briefings in bioinformatics, 2018 - academic.oup.com
Analogous to genomic sequence alignment that allows for across-species transfer of
biological knowledge between conserved sequence regions, biological network alignment …

Challenges and limitations of biological network analysis

M Milano, G Agapito, M Cannataro - BioTech, 2022 - mdpi.com
High-Throughput technologies are producing an increasing volume of data that needs large
amounts of data storage, effective data models and efficient, possibly parallel analysis …

Understanding complex systems through differential causal networks

A Defilippo, FM Giorgi, P Veltri, PH Guzzi - Scientific Reports, 2024 - nature.com
In the evolving landscape of data science and computational biology, Causal Networks
(CNs) have emerged as a robust framework for modelling causal relationships among …

A method based on temporal embedding for the pairwise alignment of dynamic networks

P Cinaglia, M Cannataro - Entropy, 2023 - mdpi.com
In network analysis, real-world systems may be represented via graph models, where nodes
and edges represent the set of biological objects (eg, genes, proteins, molecules) and their …

Visualization of protein interaction networks: problems and solutions

G Agapito, PH Guzzi, M Cannataro - BMC bioinformatics, 2013 - Springer
Background Visualization concerns the representation of data visually and is an important
task in scientific research. Protein-protein interactions (PPI) are discovered using either wet …

Temporal networks in biology and medicine: a survey on models, algorithms, and tools

MM Hosseinzadeh, M Cannataro, PH Guzzi… - … Modeling Analysis in …, 2022 - Springer
The use of static graphs for modelling and analysis of biological and biomedical data plays a
key role in biomedical research. However, many real-world scenarios present dynamic …